Relative bioequivalence evaluation of two oral atomoxetine hydrochloride capsules: a single dose, randomized, open-label, 2-period crossover study in healthy Chinese volunteers under fasting conditions

• Published in: Drug research (Stuttgart) Vol. 63; no. 11; p. 564
• Main Authors: Shang, D-W, Guo, W, Zhou, F-C, Wang, X-P, Li, A-N, Zhang, L, Li, W-B, Lu, W, Wang, C-Y
• Format: Journal Article
• Language: English
• Published: Germany 01.11.2013
• Subjects: Administration, Oral; Adrenergic Uptake Inhibitors - pharmacokinetics; Adult; Area Under Curve; Atomoxetine Hydrochloride; Capsules; Cross-Over Studies; Fasting; Humans; Male; Propylamines - pharmacokinetics; Therapeutic Equivalency; Young Adult

To evaluate the bioequivalence of a new formulation of atomoxetine hydrochloride (CAS 82248-59-7) capsules (test) and an available branded capsules (reference) after administration of a single 40 mg dose, randomized, open-label, 2-period crossover study was conducted in 22 healthy male Chinese subje...