The Mannich reaction of hydrazones: improved reactivity under solvent-free conditions
The Mannich reaction of hydrazones can be performed without solvent by simply mixing the hydrazone with two to three equivalents of a secondary amine and formaldehyde. Best yields and conditions are obtained with -nitro substituted arylhydrazones. These conditions allow the efficient coupling of sim...
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Published in | Green chemistry : an international journal and green chemistry resource : GC Vol. 5; no. 4; pp. 477 - 479 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
01.01.2003
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Online Access | Get full text |
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