Response to Toi et al. (doi: 10.1089/neu.2018.5821): Determining if Cerebrospinal Fluid Prevent Recurrence of Chronic Subdural Hematoma: A Multi-Center Prospective Randomized Clinical Trial

• Published in: Journal of neurotrauma Vol. 36; no. 7; pp. 1192 - 1193
• Main Authors: Adachi, Akihiko, Higuchi, Yoshinori
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.04.2019
• Subjects: Bias; Blood; Brain; Cerebrospinal fluid; Clinical trials; Dura mater; Hematoma; Hematoma, Subdural, Chronic; Hospitals; Humans; Lavage; Meninges; Myocardial infarction; Prospective Studies; Recurrence; Surgery; Japan
• ISSN: 0897-7151; 1557-9042
• DOI: 10.1089/neu.2018.6032

Akihiko Adachi, MD, PhD, Department of Neurological Surgery, Chiba University, 1-8-1 Inohana, Chiba 260-8670, Japan adachi-cib@umin.ac.jp Dear Editor: With great interest, we read the recent article by Toi and colleagues concerning their multi-center prospective randomized clinical trial, which compared the recurrence rates of chronic subdural hematoma (CSDH) following the administration of two irrigation solutions: normal saline (NS) or artificial cerebrospinal fluid (ACF).1 Their study verified that irrigation with ACF is not superior relative to that with NS. [...]as ACF requires more time to prepare than NS, it may also help to alleviate the workload of nurses during surgery. Figure 2 was mislabeled; the red and blue lines should correspond to the ACF and NS groups, respectively. [...]in the “Evaluation of Safety” subsection of the Results, the patients who died from myocardial infarction and pneumonia belong to ACF and NS groups, respectively.