Assessing the impact of prophylactic anidulafungin during remission induction of acute myeloid leukemia – A propensity-score matching analysis

• Published in: Journal de mycologie médicale Vol. 33; no. 4; p. 101434
• Main Authors: Silva, Wellington Fernandes da, Mendes, Fernanda Rodrigues, Melo, Raphael da Costa Bandeira de, Velloso, Elvira Deolinda Rodrigues Pereira, Rocha, Vanderson, Rego, Eduardo Magalhaes
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.11.2023
• Subjects: Acute myeloid leukemia; Adult; Anidulafungin; Antifungal Agents - therapeutic use; Antifungal prophylaxis; Fluconazole - therapeutic use; Fungal infection; Humans; Intensive chemotherapy; Leukemia, Myeloid, Acute - complications; Leukemia, Myeloid, Acute - drug therapy; Propensity Score; Remission Induction; Retrospective Studies; Antifungal prophylaxis; Intensive chemotherapy; Anidulafungin; Acute myeloid leukemia; Fungal infection; Remission induction
• ISSN: 1156-5233; 1773-0449; 1773-0449
• DOI: 10.1016/j.mycmed.2023.101434

Invasive fungal infection (IFI) accounts for substantial morbidity during the treatment of acute myeloid leukemia (AML) in adults. Antifungal prophylaxis (AP) is needed during intensive chemotherapy, and posaconazole is not widely available. In this study, we aimed to examine the impact of prophylac...