Differential Impact of Adolescent or Adult Stress on Behavior and Cortical Parvalbumin Interneurons and Perineuronal Nets in Male and Female Mice

• Published in: The international journal of neuropsychopharmacology Vol. 27; no. 10; p. 1
• Main Authors: Santos-Silva, Thamyris, Souza, Beatriz Kinchin, Colodete, Débora Akemi Endo, Campos, Lara Ramos, Lima, Thaís Santos Almeida, Guimarães, Francisco S, Gomes, Felipe V
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.10.2024
• Subjects: Age Factors; Animals; Anxiety - metabolism; Behavior, Animal - physiology; Female; Interneurons; Interneurons - metabolism; Male; Mice; Mice, Inbred C57BL; Parvalbumins - metabolism; Physiological aspects; Prefrontal Cortex - metabolism; Psychological aspects; Psychological research; Sex Characteristics; Sex differences (Psychology); Social Behavior; Stress (Psychology); Stress, Psychological - metabolism; Brazil; individual variability; neurodevelopment; sex differences; GABA interneurons

Abstract Background Stress has become a common public health concern, contributing to the rising prevalence of psychiatric disorders. Understanding the impact of stress considering critical variables, such as age, sex, and individual differences, is of the utmost importance for developing effective...