Gas chromatography mass spectrometry analysis of carboxyethyl-hydroxychroman metabolites of α- and γ-tocopherol in human plasma

• Published in: Free radical biology & medicine Vol. 32; no. 4; pp. 333 - 340
• Main Authors: Galli, Francesco, Lee, Rosalind, Dunster, Christina, Kelly, Frank J
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.02.2002
• Subjects: alpha-Tocopherol - blood; Carboxyethyl-hydroxychroman; CEHC; Chromans - analysis; Chromans - metabolism; Chromatography, High Pressure Liquid; Dietary Supplements; Free Radicals; gamma-Tocopherol - blood; Gas Chromatography-Mass Spectrometry - methods; GCMS; Humans; Plasma; Propionates - analysis; Propionates - metabolism; Time Factors; Vitamin E; Vitamin E - metabolism; Vitamin E metabolites; Vitamin E metabolites; Plasma; Carboxyethyl-hydroxychroman; CEHC; GCMS; Free radicals; Vitamin E

Alpha- and gamma-tocopherol (α- and γ-T, respectively) metabolite analysis is of key relevance in the study of vitamin E metabolism. Whilst there is information on urinary excretion of the two major metabolites of these vitamin E homologues, namely the 2,5,7,8-tetramethyl-2-(β-carboxyethyl)-6-hydrox...