Time-varying compartmental models capture hours-scale variation in the elimination kinetics of vancomycin in rats - McDonough, Matthew H; Gerson, Julian; Kippin, Tod; Meiring, Wendy; Plaxco, Kevin W (British journal of pharmacology, 2025)
Keywords: Animals; Anti-Bacterial Agents - blood; Anti-Bacterial Agents - pharmacokinetics; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Time Factors; Vancomycin - blood; Vancomycin - pharmacokinetics; compartment models; renal function; animal models; Bayesian information criterion; nonlinear least squares regression