Stability of floxuridine and leucovorin calcium admixtures for intraperitoneal administration

• Published in: American journal of hospital pharmacy Vol. 46; no. 5; p. 985
• Main Authors: Smith, J A, Morris, A, Duafala, M E, Bertino, J R, Markman, M, Kleinberg, M
• Format: Journal Article
• Language: English
• Published: United States 01.05.1989
• Subjects: Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Drug Storage; Floxuridine - administration & dosage; Floxuridine - analysis; Injections, Intraperitoneal; Leucovorin - administration & dosage; Leucovorin - analysis; Temperature

The stability of floxuridine and leucovorin calcium in admixtures of 0.9% sodium chloride injection at various concentrations, temperature conditions, and time points was determined. Admixtures of floxuridine and leucovorin calcium were prepared in 1-L plastic bags containing 0.9% sodium chloride in...