A comparative study of the hypolipidemic effects and mechanisms of action of Laminaria japonica - and Ascophyllum nodosum -derived fucoidans in apolipoprotein E-deficient mice

• Published in: Food & function Vol. 15; no. 11; pp. 5955 - 5971
• Main Authors: Liu, Tian, Wang, Xue, Wang, Yan-Ming, Sui, Feng-Rong, Zhang, Xue-Ying, Liu, Hai-Di, Ma, Dong-Yue, Liu, Xiao-Xiao, Guo, Shou-Dong
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 04.06.2024
• Subjects: Algae; Apolipoprotein E; Apolipoproteins; Arteriosclerosis; Ascophyllum nodosum; Atherosclerosis; Cardiovascular diseases; Chemical analysis; Cholesterol; Comparative studies; Fucoidan; Galactose; Intestine; Laminaria japonica; Lipids; Peroxisome proliferator-activated receptors; Receptors; Scavenger receptors; Seaweeds; Signal transduction; Small intestine; Species diversity; Triglycerides; Western blotting

The structural characteristics of fucoidans exhibit species and regional diversity. Previous studies have demonstrated that - and -derived fucoidans have type I and type II fucosyl chains, respectively. These chemical differences may contribute to distinct hypolipidemic effects and mechanisms of act...