Effect of Combined Low Dose Human Gonadotropic Hormone, Follicle Stimulating Hormone, and Testosterone Therapy (LFT Regimen) Versus Conventional High Dose Human Gonadotropic Hormone and Follicle Stimulating Hormone on Spermatogenesis and Biomarkers in Men With Hypogonadotropic Hypogonadism

• Published in: Endocrine practice Vol. 30; no. 10; p. 978
• Main Authors: Singhania, Nikhil, Devi, Konsam Biona, Kaur, Japleen, Bhansali, Anil, Gorsi, Ujjwal, Sachdeva, Naresh, Arora, Sunil, Rai, Ashutosh, Walia, Rama
• Format: Journal Article
• Language: English
• Published: United States 01.10.2024
• Subjects: Adult; Anti-Mullerian Hormone - blood; Biomarkers - blood; Chorionic Gonadotropin - administration & dosage; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follicle Stimulating Hormone - administration & dosage; Follicle Stimulating Hormone - blood; Humans; Hypogonadism - blood; Hypogonadism - drug therapy; Male; Pilot Projects; Spermatogenesis - drug effects; Testosterone - administration & dosage; Testosterone - blood; Testosterone - therapeutic use; Young Adult; spermatogenesis; anti-mullerian hormone; Inhibin B; hypogonadotropic hypogonadism

In male congenital hypogonadotropic hypogonadism (CHH), it was observed that lower dose human gonadotropic hormone (hCG) can maintain normal intratesticular testosterone levels. We propose this study to compare the low-dose hCG, follicle stimulating hormone (FSH), and Testosterone (T) [LFT Regimen]...