High-risk cutaneous squamous cell carcinoma of the head and neck : Results from 266 treated patients with metastatic lymph node disease

• Published in: Cancer Vol. 106; no. 11; pp. 2389 - 2396
• Main Authors: VENESS, Michael J, PALME, Carsten E, MORGAN, Gary J
• Format: Journal Article
• Language: English
• Published: New York, NY Wiley-Liss 01.06.2006
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Carcinoma, Squamous Cell - radiotherapy; Carcinoma, Squamous Cell - secondary; Carcinoma, Squamous Cell - surgery; Female; Head and Neck Neoplasms - pathology; Head and Neck Neoplasms - radiotherapy; Head and Neck Neoplasms - surgery; Humans; Lymphatic Metastasis; Male; Medical sciences; Middle Aged; Neoplasm Recurrence, Local - pathology; Otorhinolaryngology (head neck, general aspects and miscellaneous); Otorhinolaryngology. Stomatology; Prospective Studies; Risk Factors; Skin Neoplasms - pathology; Skin Neoplasms - radiotherapy; Skin Neoplasms - surgery; Tumors; Human; cutaneous; High risk; Squamous cell carcinoma; Lymph node; Malignant tumor; Metastasis; metastases; Cancerology; Treatment; lymph nodes; Head and neck; ENT disease; Advanced stage; Skin; Head and neck carcinoma

Most patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck (HN) are at low-risk (<5%) of developing metastatic SCC to regional lymph nodes. However, patients with unfavorable clinicopathologic factors often are under appreciated by clinicians but remain at higher risk for de...