Visual functions in non-overlapping visual field defects: dichoptic experiments in healthy subjects with simulated scotomas
In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term n...
Saved in:
| Published in | Vision research (Oxford) Vol. 235; p. 108666 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.10.2025
|
| Online Access | Get full text |
Cover
Loading…
| Abstract | In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term neural adaptation and by acute sensory effects. These two components cannot be disentangled easily in glaucoma patients, but the latter component can be isolated with simulated visual field defects in healthy subjects. Therefore, the aim of this study was to find out if simulated non-overlapping visual field defects (NOVFDs) can hamper certain aspects of visual perception in healthy subjects. We included 10 healthy subjects in this cross-sectional, observational study. Subjects underwent psychophysical experiments targeting contrast sensitivity, motion perception (line motion and coherent dot motion), and shape recognition. Experiments were done in three different viewing conditions using a stereoscope: (1) binocularly, (2) with simulated NOVFDs, and (3) monocularly. The NOVFDs viewing condition resulted in a decreased performance across all tested aspects of visual perception, when compared to the binocular viewing condition. The NOVFDs viewing condition resulted in a poorer performance in shape recognition compared to the monocular viewing condition. No other differences were observed between these two viewing conditions. Our results show that simulated NOVFDs impair certain visual functions. This contributes to the basic understanding of visual perception in healthy subjects and acts as a first step in the understanding of the relationship between disease stage and the visual problems that glaucoma patients may experience. |
|---|---|
| AbstractList | In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term neural adaptation and by acute sensory effects. These two components cannot be disentangled easily in glaucoma patients, but the latter component can be isolated with simulated visual field defects in healthy subjects. Therefore, the aim of this study was to find out if simulated non-overlapping visual field defects (NOVFDs) can hamper certain aspects of visual perception in healthy subjects. We included 10 healthy subjects in this cross-sectional, observational study. Subjects underwent psychophysical experiments targeting contrast sensitivity, motion perception (line motion and coherent dot motion), and shape recognition. Experiments were done in three different viewing conditions using a stereoscope: (1) binocularly, (2) with simulated NOVFDs, and (3) monocularly. The NOVFDs viewing condition resulted in a decreased performance across all tested aspects of visual perception, when compared to the binocular viewing condition. The NOVFDs viewing condition resulted in a poorer performance in shape recognition compared to the monocular viewing condition. No other differences were observed between these two viewing conditions. Our results show that simulated NOVFDs impair certain visual functions. This contributes to the basic understanding of visual perception in healthy subjects and acts as a first step in the understanding of the relationship between disease stage and the visual problems that glaucoma patients may experience.In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term neural adaptation and by acute sensory effects. These two components cannot be disentangled easily in glaucoma patients, but the latter component can be isolated with simulated visual field defects in healthy subjects. Therefore, the aim of this study was to find out if simulated non-overlapping visual field defects (NOVFDs) can hamper certain aspects of visual perception in healthy subjects. We included 10 healthy subjects in this cross-sectional, observational study. Subjects underwent psychophysical experiments targeting contrast sensitivity, motion perception (line motion and coherent dot motion), and shape recognition. Experiments were done in three different viewing conditions using a stereoscope: (1) binocularly, (2) with simulated NOVFDs, and (3) monocularly. The NOVFDs viewing condition resulted in a decreased performance across all tested aspects of visual perception, when compared to the binocular viewing condition. The NOVFDs viewing condition resulted in a poorer performance in shape recognition compared to the monocular viewing condition. No other differences were observed between these two viewing conditions. Our results show that simulated NOVFDs impair certain visual functions. This contributes to the basic understanding of visual perception in healthy subjects and acts as a first step in the understanding of the relationship between disease stage and the visual problems that glaucoma patients may experience. In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term neural adaptation and by acute sensory effects. These two components cannot be disentangled easily in glaucoma patients, but the latter component can be isolated with simulated visual field defects in healthy subjects. Therefore, the aim of this study was to find out if simulated non-overlapping visual field defects (NOVFDs) can hamper certain aspects of visual perception in healthy subjects. We included 10 healthy subjects in this cross-sectional, observational study. Subjects underwent psychophysical experiments targeting contrast sensitivity, motion perception (line motion and coherent dot motion), and shape recognition. Experiments were done in three different viewing conditions using a stereoscope: (1) binocularly, (2) with simulated NOVFDs, and (3) monocularly. The NOVFDs viewing condition resulted in a decreased performance across all tested aspects of visual perception, when compared to the binocular viewing condition. The NOVFDs viewing condition resulted in a poorer performance in shape recognition compared to the monocular viewing condition. No other differences were observed between these two viewing conditions. Our results show that simulated NOVFDs impair certain visual functions. This contributes to the basic understanding of visual perception in healthy subjects and acts as a first step in the understanding of the relationship between disease stage and the visual problems that glaucoma patients may experience. |
| ArticleNumber | 108666 |
| Author | Jansonius, Nomdo M. Gazanchian, Mehrdad Cornelissen, Frans W. |
| Author_xml | – sequence: 1 givenname: Mehrdad orcidid: 0000-0002-4406-1476 surname: Gazanchian fullname: Gazanchian, Mehrdad email: m.gazanchian@umcg.nl organization: Laboratory of Experimental Ophthalmology, Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands – sequence: 2 givenname: Frans W. surname: Cornelissen fullname: Cornelissen, Frans W. email: f.w.cornelissen@umcg.nl organization: Laboratory of Experimental Ophthalmology, Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands – sequence: 3 givenname: Nomdo M. surname: Jansonius fullname: Jansonius, Nomdo M. email: n.m.jansonius@umcg.nl organization: Laboratory of Experimental Ophthalmology, Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40763500$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUFv1DAQhS1URLeFf4CQj1yyOE48TjggoQpapEpcaK-WY09YrxI7xM6Wij-Plyw99jTS6Hszeu9dkDMfPBLytmTbkpXwYb89uDhj3HLGRV41APCCbMpGNoWAGs7IhrGaF9A27Tm5iHHPGJOCt6_Iec0kVIKxDflz7-KiB9ov3iQXfKTO0_ypCAecBz1Nzv-khxPjcLDUYo8mxY_UOrMLU3KG4u8JZzeiT__kO9RD2j3SuHT7I0ofXNrR6MZl0AktjSakMOr4mrzs9RDxzWlekruvX35c3RS336-_XX2-LQyXNRSma0opbM1RWImMgcy2eqtF2YhOCG4aC1UnwUILWuQYem7KukLZCgDNsLok79e70xx-LRiTGl00OAzaY1iiqnglczYN1Bl9d0KXbkSrpmxLz4_qf2AZqFfAzCHm-PsnpGTq2Ivaq7UXdexFrb1k2adVhtnnweGsonHoDVo354iUDe75A38B362Zkw |
| Cites_doi | 10.1016/0042-6989(95)00325-8 10.1167/iovs.10-5910 10.1038/nrn701 10.1068/p070195 10.1068/p7716 10.3758/BF03202828 10.3758/BF03194544 10.1038/nrn1869 10.1068/p251137 10.1068/p120447 10.3758/BF03214282 10.1002/cne.24871 10.3368/aoj.54.1.112 10.1016/j.ophtha.2007.08.037 10.1163/156856897X00357 10.1111/j.1475-1313.1997.tb00030.x 10.1068/p090577 10.1016/0042-6989(78)90045-7 10.1167/jov.23.10.15 10.1038/eye.1991.129 10.1016/0042-6989(94)90253-4 10.1016/0042-6989(84)90064-6 10.1167/tvst.13.10.27 10.1016/j.visres.2007.02.005 10.1167/iovs.07-0194 10.1016/j.visres.2019.10.012 10.1016/0042-6989(93)90156-Q 10.1016/j.visres.2017.04.009 10.1016/j.visres.2011.02.001 10.1111/j.1755-3768.1994.tb07187.x 10.1167/3.5.5 10.1016/0042-6989(91)90138-U 10.1016/j.cortex.2012.12.005 10.1001/jamaophthalmol.2014.4908 10.1111/j.1475-1313.2004.00223.x 10.1016/S0042-6989(98)00109-6 10.1523/JNEUROSCI.12-12-04745.1992 10.1167/iovs.62.12.9 10.1016/0042-6989(92)90097-3 10.1186/s12886-019-1176-0 |
| ContentType | Journal Article |
| Copyright | 2025 The Authors Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved. |
| Copyright_xml | – notice: 2025 The Authors – notice: Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved. |
| DBID | 6I. AAFTH AAYXX CITATION NPM 7X8 |
| DOI | 10.1016/j.visres.2025.108666 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic PubMed |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Anatomy & Physiology |
| EISSN | 1878-5646 |
| ExternalDocumentID | 40763500 10_1016_j_visres_2025_108666 S0042698925001270 |
| Genre | Journal Article |
| GroupedDBID | --- --K --M -~X .55 .GJ .~1 0R~ 123 1B1 1RT 1~. 1~5 29Q 4.4 457 4G. 53G 5RE 5VS 6I. 6PF 7-5 71M 8P~ 9JM AABNK AAEDT AAEDW AAFTH AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAWTL AAXKI AAXLA AAXUO AAYWO ABBQC ABCQJ ABDPE ABFNM ABFRF ABIVO ABJNI ABMAC ABMZM ABWVN ABXDB ACDAQ ACGFO ACGFS ACIEU ACIUM ACNCT ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADIYS ADMUD ADNMO ADVLN AEBSH AEFWE AEIPS AEKER AENEX AETEA AEUPX AEXQZ AFFNX AFJKZ AFPUW AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGWIK AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV C45 CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HEA HMK HMO HMQ HVGLF HZ~ H~9 IHE IXB J1W K-O KOM L7B LZ2 M29 M2V M41 MO0 MOBAO N9A O-L O9- OAUVE OK1 OVD OZT P-8 P-9 P2P PC. Q38 R2- RNS ROL RPZ SAE SCC SDF SDG SDP SES SEW SNS SPCBC SSH SSN SSZ T5K TEORI TN5 WUQ X7M XOL XPP ZGI ZKB ZMT ~G- AAYXX AGRNS CITATION RIG NPM 7X8 |
| ID | FETCH-LOGICAL-c2746-cb8175d42e5d7e0067042fda5185b552c8d63b76d696a5866f2c143e79566a0e3 |
| IEDL.DBID | .~1 |
| ISSN | 0042-6989 1878-5646 |
| IngestDate | Wed Aug 06 19:20:17 EDT 2025 Thu Aug 07 06:12:01 EDT 2025 Thu Aug 07 06:50:16 EDT 2025 Sat Aug 30 17:12:31 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Language | English |
| License | This is an open access article under the CC BY license. Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c2746-cb8175d42e5d7e0067042fda5185b552c8d63b76d696a5866f2c143e79566a0e3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0002-4406-1476 |
| OpenAccessLink | https://www.sciencedirect.com/science/article/pii/S0042698925001270 |
| PMID | 40763500 |
| PQID | 3237000864 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_3237000864 pubmed_primary_40763500 crossref_primary_10_1016_j_visres_2025_108666 elsevier_sciencedirect_doi_10_1016_j_visres_2025_108666 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-10-01 |
| PublicationDateYYYYMMDD | 2025-10-01 |
| PublicationDate_xml | – month: 10 year: 2025 text: 2025-10-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Vision research (Oxford) |
| PublicationTitleAlternate | Vision Res |
| PublicationYear | 2025 |
| Publisher | Elsevier Ltd |
| Publisher_xml | – name: Elsevier Ltd |
| References | Stoutenbeek, Heeg, Jansonius (b0155) 2004 Baker, Meese, Mansouri, Hess (b0010) 2007; 48 Haak, Langers, Renken, van Dijk, Borgstein, Cornelissen (b0065) 2014; 56 Legge (b0105) 1984; 24 Bearse, Freeman (b0015) 1994; 34 Jansonius, Stam, de Jong, Pijpker (b0080) 2014; 43 Roper-Hall (b0135) 2004 Gazanchian, Mehrdad, and Nomdo M. Jansonius. 2024. Effect of non-overlapping visual field defects on vision related quality of life in glaucoma. Ophthalmology. Glaucoma, February. https://doi.org/10.1016/j.ogla.2024.01.007. Mokri, da Silva, Castanheira, Landry, Mendola (b0125) 2023; 23 Scase, Braddick, Raymond (b0150) 1996; 36 Chow-Wing-Bom, Dekker, Jones (b0045) 2020; 169 Brainard (b0030) 1997 Rose (b0145) 1980; 9 Taylor, Misson, Moseley (b0160) 1991; 5 De Valois, De Valois (b0050) 1991; 31 McKee, Levi, Anthony Movshon (b0120) 2003; 3 Wilson, Wilkinson (b0195) 1998; 38 Hess, Hutchinson, Ledgeway, Mansouri (b0070) 2007; 47 Rose (b0140) 1978; 7 McElvanney, Moseley, Jones (b0110) 1994; 72 Field, Hayes, Hess (b0055) 1993; 33 Knudsen (b0095) 2020; 528 Komatsu (b0100) 2006; 7 Wichmann, Hill (b0190) 2001; 63 McKean-Cowdin, Roberta, Ying Wang, Joanne Wu, Stanley P. Azen, Rohit Varma, and Los Angeles Latino Eye Study Group. 2008. Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino eye study. Ophthalmology 115 (6) 941–48.e1. Blake, Sloane, Fox (b0025) 1981; 30 Cheng, Guo, Chen, Ko, Huang, Liu (b0040) 2015; 133 Jansonius, Kooijman (b0085) 1997; 17 Wolfe (b0200) 1983; 12 Qian, Brascamp, Liu (b0130) 2017; 136 Wade (b0175) 1996; 25 João, Scanferla, Jansonius (b0090) 2021; 62 Watson, Pelli (b0185) 1983 Abadi, Jeffery, Murphy (b0005) 2011; 52 Britten, Shadlen, Newsome, Movshon (b0035) 1992; 12 Watamaniuk, Sekuler (b0180) 1992; 32 Howell, Hess (b0075) 1978; 18 Thompson, Richard, Churan, Hess, Aaen-Stockdale, Pack (b0165) 2011; 51 Blake, Logothetis (b0020) 2002; 3 Volbrecht, Shrago, Schefrin, Werner (b0170) 2000; 26 Yang, Shi, Tang (b0205) 2019; 19 Watamaniuk (10.1016/j.visres.2025.108666_b0180) 1992; 32 Field (10.1016/j.visres.2025.108666_b0055) 1993; 33 McKee (10.1016/j.visres.2025.108666_b0120) 2003; 3 Thompson (10.1016/j.visres.2025.108666_b0165) 2011; 51 Haak (10.1016/j.visres.2025.108666_b0065) 2014; 56 Scase (10.1016/j.visres.2025.108666_b0150) 1996; 36 Stoutenbeek (10.1016/j.visres.2025.108666_b0155) 2004 Wolfe (10.1016/j.visres.2025.108666_b0200) 1983; 12 Hess (10.1016/j.visres.2025.108666_b0070) 2007; 47 Volbrecht (10.1016/j.visres.2025.108666_b0170) 2000; 26 Legge (10.1016/j.visres.2025.108666_b0105) 1984; 24 Wilson (10.1016/j.visres.2025.108666_b0195) 1998; 38 Brainard (10.1016/j.visres.2025.108666_b0030) 1997 Komatsu (10.1016/j.visres.2025.108666_b0100) 2006; 7 Roper-Hall (10.1016/j.visres.2025.108666_b0135) 2004 Chow-Wing-Bom (10.1016/j.visres.2025.108666_b0045) 2020; 169 Blake (10.1016/j.visres.2025.108666_b0025) 1981; 30 Howell (10.1016/j.visres.2025.108666_b0075) 1978; 18 Jansonius (10.1016/j.visres.2025.108666_b0085) 1997; 17 Baker (10.1016/j.visres.2025.108666_b0010) 2007; 48 Knudsen (10.1016/j.visres.2025.108666_b0095) 2020; 528 Mokri (10.1016/j.visres.2025.108666_b0125) 2023; 23 Rose (10.1016/j.visres.2025.108666_b0140) 1978; 7 10.1016/j.visres.2025.108666_b0115 Yang (10.1016/j.visres.2025.108666_b0205) 2019; 19 Watson (10.1016/j.visres.2025.108666_b0185) 1983 Bearse (10.1016/j.visres.2025.108666_b0015) 1994; 34 Blake (10.1016/j.visres.2025.108666_b0020) 2002; 3 McElvanney (10.1016/j.visres.2025.108666_b0110) 1994; 72 Rose (10.1016/j.visres.2025.108666_b0145) 1980; 9 10.1016/j.visres.2025.108666_b0060 Abadi (10.1016/j.visres.2025.108666_b0005) 2011; 52 João (10.1016/j.visres.2025.108666_b0090) 2021; 62 Jansonius (10.1016/j.visres.2025.108666_b0080) 2014; 43 Qian (10.1016/j.visres.2025.108666_b0130) 2017; 136 Wade (10.1016/j.visres.2025.108666_b0175) 1996; 25 Taylor (10.1016/j.visres.2025.108666_b0160) 1991; 5 Wichmann (10.1016/j.visres.2025.108666_b0190) 2001; 63 De Valois (10.1016/j.visres.2025.108666_b0050) 1991; 31 Cheng (10.1016/j.visres.2025.108666_b0040) 2015; 133 Britten (10.1016/j.visres.2025.108666_b0035) 1992; 12 |
| References_xml | – volume: 56 start-page: 14 year: 2014 end-page: 25 ident: b0065 article-title: Abnormal visual field maps in human cortex: A mini-review and a case report publication-title: Cortex; A Journal Devoted to the Study of the Nervous System and Behavior – volume: 36 start-page: 2579 year: 1996 end-page: 2586 ident: b0150 article-title: What is noise for the motion system? publication-title: Vision Research – volume: 26 start-page: S32 year: 2000 end-page: S35 ident: b0170 article-title: Ricco’s areas for S- and L-cone mechanisms across the retina publication-title: Color Research and Application – volume: 34 start-page: 19 year: 1994 end-page: 29 ident: b0015 article-title: Binocular summation in orientation discrimination depends on stimulus contrast and duration publication-title: Vision Research – volume: 33 start-page: 173 year: 1993 end-page: 193 ident: b0055 article-title: Contour integration by the human visual system: evidence for a local ‘association field. publication-title: Vision Research – volume: 17 start-page: 128 year: 1997 end-page: 132 ident: b0085 article-title: The effect of defocus on edge contrast sensitivity publication-title: Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) – year: 2004 ident: b0135 article-title: The ‘Worth’ of the worth four dot test publication-title: American Orthoptic Journal – volume: 31 start-page: 1619 year: 1991 end-page: 1626 ident: b0050 article-title: Vernier acuity with stationary moving gabors publication-title: Vision Research – volume: 72 start-page: 606 year: 1994 end-page: 611 ident: b0110 article-title: Binocular Inhibition of visual performance in patients with cataract. The influence of test reliability publication-title: Acta Ophthalmologica – volume: 24 start-page: 385 year: 1984 end-page: 394 ident: b0105 article-title: Binocular contrast summation–II. Quadratic summation publication-title: Vision Research – volume: 136 start-page: 15 year: 2017 end-page: 20 ident: b0130 article-title: On the functional order of binocular rivalry and blind spot filling-in publication-title: Vision Research – volume: 43 start-page: 1329 year: 2014 end-page: 1340 ident: b0080 article-title: Quantitative analysis of illusory movement: spatial filtering and line localization in the human visual system publication-title: Perception – reference: Gazanchian, Mehrdad, and Nomdo M. Jansonius. 2024. Effect of non-overlapping visual field defects on vision related quality of life in glaucoma. Ophthalmology. Glaucoma, February. https://doi.org/10.1016/j.ogla.2024.01.007. – volume: 63 start-page: 1293 year: 2001 end-page: 1313 ident: b0190 article-title: The psychometric function: I. Fitting, sampling, and goodness of fit publication-title: Perception & Psychophysics – volume: 133 start-page: 269 year: 2015 end-page: 275 ident: b0040 article-title: Patient-reported vision-related quality of life differences between superior and inferior hemifield visual field defects in primary open-angle glaucoma publication-title: JAMA Ophthalmology – year: 2004 ident: b0155 article-title: Frequency doubling perimetry screening mode compared to the full-threshold mode publication-title: Ophthalmic and Physiological Optics – volume: 528 start-page: 2888 year: 2020 end-page: 2901 ident: b0095 article-title: Evolution of neural processing for visual perception in vertebrates publication-title: The Journal of Comparative Neurology – volume: 25 start-page: 1137 year: 1996 end-page: 1175 ident: b0175 article-title: Descriptions of visual phenomena from aristotle to wheatstone publication-title: Perception – volume: 30 start-page: 266 year: 1981 end-page: 276 ident: b0025 article-title: Further developments in binocular summation publication-title: Perception & Psychophysics – volume: 18 start-page: 369 year: 1978 end-page: 374 ident: b0075 article-title: The functional area for summation to threshold for sinusoidal gratings publication-title: Vision Research – volume: 9 start-page: 577 year: 1980 end-page: 580 ident: b0145 article-title: The binocular: monocular sensitivity ratio for movement detection varies with temporal frequency publication-title: Perception – volume: 12 start-page: 447 year: 1983 end-page: 456 ident: b0200 article-title: Influence of spatial frequency, luminance, and duration on binocular rivalry and abnormal fusion of briefly presented dichoptic stimuli publication-title: Perception – year: 1997 ident: b0030 article-title: The psychophysics toolbox publication-title: Spatial Vision – volume: 23 start-page: 15 year: 2023 ident: b0125 article-title: Effects of interocular grouping demands on binocular rivalry publication-title: Journal of Vision – volume: 48 start-page: 5332 year: 2007 end-page: 5538 ident: b0010 article-title: Binocular summation of contrast remains intact in strabismic amblyopia publication-title: Investigative Ophthalmology & Visual Science – volume: 3 start-page: 13 year: 2002 end-page: 21 ident: b0020 article-title: Visual competition publication-title: Nature Reviews. Neuroscience – volume: 62 start-page: 9 year: 2021 ident: b0090 article-title: Binocular interactions in glaucoma patients with nonoverlapping visual field defects: Contrast summation, rivalry, and phase combination publication-title: Investigative Ophthalmology & Visual Science – volume: 7 start-page: 220 year: 2006 end-page: 231 ident: b0100 article-title: The neural mechanisms of perceptual filling-in publication-title: Nature Reviews. Neuroscience – volume: 3 start-page: 380 year: 2003 end-page: 405 ident: b0120 article-title: The pattern of visual deficits in amblyopia publication-title: Journal of Vision – reference: McKean-Cowdin, Roberta, Ying Wang, Joanne Wu, Stanley P. Azen, Rohit Varma, and Los Angeles Latino Eye Study Group. 2008. Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino eye study. Ophthalmology 115 (6) 941–48.e1. – volume: 52 start-page: 541 year: 2011 end-page: 558 ident: b0005 article-title: Awareness and filling-in of the human blind spot: Linking psychophysics with retinal topography publication-title: Investigative Ophthalmology & Visual Science – volume: 38 start-page: 2933 year: 1998 end-page: 2947 ident: b0195 article-title: Detection of global structure in glass patterns: implications for form vision publication-title: Vision Research – volume: 12 start-page: 4745 year: 1992 end-page: 4765 ident: b0035 article-title: The analysis of visual motion: A comparison of neuronal and psychophysical performance publication-title: The Journal of Neuroscience: The Official Journal of the Society for Neuroscience – volume: 47 start-page: 1682 year: 2007 end-page: 1692 ident: b0070 article-title: Binocular influences on global motion processing in the human visual system publication-title: Vision Research – volume: 5 start-page: 704 year: 1991 end-page: 707 ident: b0160 article-title: Visual acuity and contrast sensitivity in cataract: Summation and inhibition of visual performance publication-title: Eye (London, England) – volume: 32 start-page: 2341 year: 1992 end-page: 2347 ident: b0180 article-title: Temporal and spatial integration in dynamic random-dot stimuli publication-title: Vision Research – volume: 19 start-page: 166 year: 2019 ident: b0205 article-title: Associations of subjective and objective clinical outcomes of visual functions with quality of life in chinese glaucoma patients: a cross-sectional study publication-title: BMC Ophthalmology – volume: 169 start-page: 49 year: 2020 end-page: 57 ident: b0045 article-title: The worse eye revisited: evaluating the impact of asymmetric peripheral vision loss on everyday function publication-title: Vision Research – volume: 51 start-page: 577 year: 2011 end-page: 584 ident: b0165 article-title: Impaired spatial and binocular summation for motion direction discrimination in strabismic amblyopia publication-title: Vision Research – volume: 7 start-page: 195 year: 1978 end-page: 200 ident: b0140 article-title: Monocular versus binocular contrast thresholds for movement and pattern publication-title: Perception – year: 1983 ident: b0185 article-title: Quest: a Bayesian adaptive psychometric method publication-title: Perception & Psychophysics – volume: 36 start-page: 2579 issue: 16 year: 1996 ident: 10.1016/j.visres.2025.108666_b0150 article-title: What is noise for the motion system? publication-title: Vision Research doi: 10.1016/0042-6989(95)00325-8 – volume: 52 start-page: 541 issue: 1 year: 2011 ident: 10.1016/j.visres.2025.108666_b0005 article-title: Awareness and filling-in of the human blind spot: Linking psychophysics with retinal topography publication-title: Investigative Ophthalmology & Visual Science doi: 10.1167/iovs.10-5910 – volume: 3 start-page: 13 issue: 1 year: 2002 ident: 10.1016/j.visres.2025.108666_b0020 article-title: Visual competition publication-title: Nature Reviews. Neuroscience doi: 10.1038/nrn701 – volume: 7 start-page: 195 issue: 2 year: 1978 ident: 10.1016/j.visres.2025.108666_b0140 article-title: Monocular versus binocular contrast thresholds for movement and pattern publication-title: Perception doi: 10.1068/p070195 – volume: 43 start-page: 1329 issue: 12 year: 2014 ident: 10.1016/j.visres.2025.108666_b0080 article-title: Quantitative analysis of illusory movement: spatial filtering and line localization in the human visual system publication-title: Perception doi: 10.1068/p7716 – year: 1983 ident: 10.1016/j.visres.2025.108666_b0185 article-title: Quest: a Bayesian adaptive psychometric method publication-title: Perception & Psychophysics doi: 10.3758/BF03202828 – volume: 63 start-page: 1293 issue: 8 year: 2001 ident: 10.1016/j.visres.2025.108666_b0190 article-title: The psychometric function: I. Fitting, sampling, and goodness of fit publication-title: Perception & Psychophysics doi: 10.3758/BF03194544 – volume: 7 start-page: 220 issue: 3 year: 2006 ident: 10.1016/j.visres.2025.108666_b0100 article-title: The neural mechanisms of perceptual filling-in publication-title: Nature Reviews. Neuroscience doi: 10.1038/nrn1869 – volume: 25 start-page: 1137 issue: 10 year: 1996 ident: 10.1016/j.visres.2025.108666_b0175 article-title: Descriptions of visual phenomena from aristotle to wheatstone publication-title: Perception doi: 10.1068/p251137 – volume: 12 start-page: 447 issue: 4 year: 1983 ident: 10.1016/j.visres.2025.108666_b0200 article-title: Influence of spatial frequency, luminance, and duration on binocular rivalry and abnormal fusion of briefly presented dichoptic stimuli publication-title: Perception doi: 10.1068/p120447 – volume: 26 start-page: S32 issue: 51 year: 2000 ident: 10.1016/j.visres.2025.108666_b0170 article-title: Ricco’s areas for S- and L-cone mechanisms across the retina publication-title: Color Research and Application – volume: 30 start-page: 266 issue: 3 year: 1981 ident: 10.1016/j.visres.2025.108666_b0025 article-title: Further developments in binocular summation publication-title: Perception & Psychophysics doi: 10.3758/BF03214282 – volume: 528 start-page: 2888 issue: 17 year: 2020 ident: 10.1016/j.visres.2025.108666_b0095 article-title: Evolution of neural processing for visual perception in vertebrates publication-title: The Journal of Comparative Neurology doi: 10.1002/cne.24871 – year: 2004 ident: 10.1016/j.visres.2025.108666_b0135 article-title: The ‘Worth’ of the worth four dot test publication-title: American Orthoptic Journal doi: 10.3368/aoj.54.1.112 – ident: 10.1016/j.visres.2025.108666_b0115 doi: 10.1016/j.ophtha.2007.08.037 – year: 1997 ident: 10.1016/j.visres.2025.108666_b0030 article-title: The psychophysics toolbox publication-title: Spatial Vision doi: 10.1163/156856897X00357 – volume: 17 start-page: 128 issue: 2 year: 1997 ident: 10.1016/j.visres.2025.108666_b0085 article-title: The effect of defocus on edge contrast sensitivity publication-title: Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) doi: 10.1111/j.1475-1313.1997.tb00030.x – volume: 9 start-page: 577 issue: 5 year: 1980 ident: 10.1016/j.visres.2025.108666_b0145 article-title: The binocular: monocular sensitivity ratio for movement detection varies with temporal frequency publication-title: Perception doi: 10.1068/p090577 – volume: 18 start-page: 369 issue: 4 year: 1978 ident: 10.1016/j.visres.2025.108666_b0075 article-title: The functional area for summation to threshold for sinusoidal gratings publication-title: Vision Research doi: 10.1016/0042-6989(78)90045-7 – volume: 23 start-page: 15 issue: 10 year: 2023 ident: 10.1016/j.visres.2025.108666_b0125 article-title: Effects of interocular grouping demands on binocular rivalry publication-title: Journal of Vision doi: 10.1167/jov.23.10.15 – volume: 5 start-page: 704 issue: Pt 6 year: 1991 ident: 10.1016/j.visres.2025.108666_b0160 article-title: Visual acuity and contrast sensitivity in cataract: Summation and inhibition of visual performance publication-title: Eye (London, England) doi: 10.1038/eye.1991.129 – volume: 34 start-page: 19 issue: 1 year: 1994 ident: 10.1016/j.visres.2025.108666_b0015 article-title: Binocular summation in orientation discrimination depends on stimulus contrast and duration publication-title: Vision Research doi: 10.1016/0042-6989(94)90253-4 – volume: 24 start-page: 385 issue: 4 year: 1984 ident: 10.1016/j.visres.2025.108666_b0105 article-title: Binocular contrast summation–II. Quadratic summation publication-title: Vision Research doi: 10.1016/0042-6989(84)90064-6 – ident: 10.1016/j.visres.2025.108666_b0060 doi: 10.1167/tvst.13.10.27 – volume: 47 start-page: 1682 issue: 12 year: 2007 ident: 10.1016/j.visres.2025.108666_b0070 article-title: Binocular influences on global motion processing in the human visual system publication-title: Vision Research doi: 10.1016/j.visres.2007.02.005 – volume: 48 start-page: 5332 issue: 11 year: 2007 ident: 10.1016/j.visres.2025.108666_b0010 article-title: Binocular summation of contrast remains intact in strabismic amblyopia publication-title: Investigative Ophthalmology & Visual Science doi: 10.1167/iovs.07-0194 – volume: 169 start-page: 49 issue: April year: 2020 ident: 10.1016/j.visres.2025.108666_b0045 article-title: The worse eye revisited: evaluating the impact of asymmetric peripheral vision loss on everyday function publication-title: Vision Research doi: 10.1016/j.visres.2019.10.012 – volume: 33 start-page: 173 issue: 2 year: 1993 ident: 10.1016/j.visres.2025.108666_b0055 article-title: Contour integration by the human visual system: evidence for a local ‘association field. publication-title: Vision Research doi: 10.1016/0042-6989(93)90156-Q – volume: 136 start-page: 15 issue: July year: 2017 ident: 10.1016/j.visres.2025.108666_b0130 article-title: On the functional order of binocular rivalry and blind spot filling-in publication-title: Vision Research doi: 10.1016/j.visres.2017.04.009 – volume: 51 start-page: 577 issue: 6 year: 2011 ident: 10.1016/j.visres.2025.108666_b0165 article-title: Impaired spatial and binocular summation for motion direction discrimination in strabismic amblyopia publication-title: Vision Research doi: 10.1016/j.visres.2011.02.001 – volume: 72 start-page: 606 issue: 5 year: 1994 ident: 10.1016/j.visres.2025.108666_b0110 article-title: Binocular Inhibition of visual performance in patients with cataract. The influence of test reliability publication-title: Acta Ophthalmologica doi: 10.1111/j.1755-3768.1994.tb07187.x – volume: 3 start-page: 380 issue: 5 year: 2003 ident: 10.1016/j.visres.2025.108666_b0120 article-title: The pattern of visual deficits in amblyopia publication-title: Journal of Vision doi: 10.1167/3.5.5 – volume: 31 start-page: 1619 issue: 9 year: 1991 ident: 10.1016/j.visres.2025.108666_b0050 article-title: Vernier acuity with stationary moving gabors publication-title: Vision Research doi: 10.1016/0042-6989(91)90138-U – volume: 56 start-page: 14 issue: July year: 2014 ident: 10.1016/j.visres.2025.108666_b0065 article-title: Abnormal visual field maps in human cortex: A mini-review and a case report publication-title: Cortex; A Journal Devoted to the Study of the Nervous System and Behavior doi: 10.1016/j.cortex.2012.12.005 – volume: 133 start-page: 269 issue: 3 year: 2015 ident: 10.1016/j.visres.2025.108666_b0040 article-title: Patient-reported vision-related quality of life differences between superior and inferior hemifield visual field defects in primary open-angle glaucoma publication-title: JAMA Ophthalmology doi: 10.1001/jamaophthalmol.2014.4908 – year: 2004 ident: 10.1016/j.visres.2025.108666_b0155 article-title: Frequency doubling perimetry screening mode compared to the full-threshold mode publication-title: Ophthalmic and Physiological Optics doi: 10.1111/j.1475-1313.2004.00223.x – volume: 38 start-page: 2933 issue: 19 year: 1998 ident: 10.1016/j.visres.2025.108666_b0195 article-title: Detection of global structure in glass patterns: implications for form vision publication-title: Vision Research doi: 10.1016/S0042-6989(98)00109-6 – volume: 12 start-page: 4745 issue: 12 year: 1992 ident: 10.1016/j.visres.2025.108666_b0035 article-title: The analysis of visual motion: A comparison of neuronal and psychophysical performance publication-title: The Journal of Neuroscience: The Official Journal of the Society for Neuroscience doi: 10.1523/JNEUROSCI.12-12-04745.1992 – volume: 62 start-page: 9 issue: 12 year: 2021 ident: 10.1016/j.visres.2025.108666_b0090 article-title: Binocular interactions in glaucoma patients with nonoverlapping visual field defects: Contrast summation, rivalry, and phase combination publication-title: Investigative Ophthalmology & Visual Science doi: 10.1167/iovs.62.12.9 – volume: 32 start-page: 2341 issue: 12 year: 1992 ident: 10.1016/j.visres.2025.108666_b0180 article-title: Temporal and spatial integration in dynamic random-dot stimuli publication-title: Vision Research doi: 10.1016/0042-6989(92)90097-3 – volume: 19 start-page: 166 issue: 1 year: 2019 ident: 10.1016/j.visres.2025.108666_b0205 article-title: Associations of subjective and objective clinical outcomes of visual functions with quality of life in chinese glaucoma patients: a cross-sectional study publication-title: BMC Ophthalmology doi: 10.1186/s12886-019-1176-0 |
| SSID | ssj0007529 |
| Score | 2.4739125 |
| Snippet | In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 108666 |
| Title | Visual functions in non-overlapping visual field defects: dichoptic experiments in healthy subjects with simulated scotomas |
| URI | https://dx.doi.org/10.1016/j.visres.2025.108666 https://www.ncbi.nlm.nih.gov/pubmed/40763500 https://www.proquest.com/docview/3237000864 |
| Volume | 235 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dS9xAEB_EQulLadW2p61sofi2GvYz6dshlWuLPlXxbdnNbtqI3om5E6Tg396ZTVIptAh9TNhNNjuT-drfzAB8kFQSpIgVLxobuWqs5kHWipO-oIJnSebQxfGJmZ2qL-f6fA0Ox1wYglUOsr-X6VlaD3cOht08uG5byvGlNMyyQiWez08pg11Z4vL9-weYh9WiGtNQaPSYPpcxXrct6iEq2i10bjmUayX-VT39y_zMaujoBTwf7Ec27Zf4EtbSfAM2p3P0na_u2B7LiM4cKt-Ap8fDwfkm_DxruxXOIzWWOY21c4aePycE56WnIg3f2e0whkBtLKYM9PjI8BE_FihYavbQDSBP71Mo71i3ChTM6RjFdFnXXlFHsBRZVy-WhD7agtOjT98OZ3zou8Br9FENr0OJRkVUIuloU87kUaKJXqNuD1qLuoxGBmuiqYzXuGuNqNHsShZ9LeOLJF_BOn5BegMsJIkWmlSVj6UKXvrgK2GkqYWWKTXlBPi43e66L6_hRtzZhevJ44g8rifPBOxIE_cHmzjUAI_MfD-S0OEfRMcifp4Wq85JIW127dQEXve0_b0WdHfRIiuK7f9-7w48o6se__cW1pc3q_QO7Zhl2M2MugtPpp-_zk5-ASBD8tk |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB5RkFouiEdbtk9XqnpzifxKwg0h0LZlOUHFzbJjp00Fu4jsIqFK_HZmnKSoUiskromdh8f2NzP-Zgbgo6SUIFkoeVbngas619zLSnHCC0p4FmVyXUyOzfhUfT3TZ0uwP8TCEK2y3_u7PT3t1v2VnX40dy6bhmJ8KQyzKBHE0_npE1hRuHypjMHn23ueR65FOcShUPMhfi6RvK4bBCLK2i10qjmUkiX-E5_-p38mHDpch7VegWR73TduwFKcbsLW3hSN54sb9oklSmfylW_C00l_cr4Fv7837QL7EY6lqcaaKUPTnxOF89xRloYf7LpvQ6w2FmJieuwyfMTPGe4sFbsvB5C6dzGUN6xdePLmtIycuqxtLqgkWAysrWZzoh89h9PDg5P9Me8LL_AKjVTDK1-gVhGUiDrkMYXyKFEHpxHcvdaiKoKRPjfBlMZpHLVaVKh3xRyNLeOyKF_AMv5B3Abmo0QVTarShUJ5J513pTDSVELLGOtiBHwYbnvZ5dewA_Hsl-3EY0k8thPPCPJBJvaveWIRAh7o-WEQocUlROcibhpni9ZKIfNk26kRvOxk--db0N5FlSzLXj36ve_h2fhkcmSPvhx_ew2rdKcjA76B5fnVIr5FpWbu36VJewetR_Rn |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Visual+functions+in+non-overlapping+visual+field+defects%3A+dichoptic+experiments+in+healthy+subjects+with+simulated+scotomas&rft.jtitle=Vision+research+%28Oxford%29&rft.au=Gazanchian%2C+Mehrdad&rft.au=Cornelissen%2C+Frans+W&rft.au=Jansonius%2C+Nomdo+M&rft.date=2025-10-01&rft.eissn=1878-5646&rft.volume=235&rft.spage=108666&rft_id=info:doi/10.1016%2Fj.visres.2025.108666&rft_id=info%3Apmid%2F40763500&rft.externalDocID=40763500 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0042-6989&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0042-6989&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0042-6989&client=summon |