Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion, and Fibrotic Burden When Administered to Patients Undergoing Coronary Artery Bypass Grafting: The Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) Trial - Karantalis, Vasileios; DiFede, Darcy L.; Gerstenblith, Gary; Pham, Si; Symes, James; Zambrano, Juan Pablo; Fishman, Joel; Pattany, Pradip; McNiece, Ian; Conte, John; Schulman, Steven; Wu, Katherine; et al. (Circulation research, 2014)
Keywords: Cardiomyopathies - therapy; Cell- and Tissue-Based Therapy - methods; Cicatrix - pathology; Cicatrix - therapy; Coronary Artery Bypass; Fibrosis - pathology; Fibrosis - therapy; Follow-Up Studies; Humans; Injections; Magnetic Resonance Imaging; Male; Mesenchymal Stem Cell Transplantation - methods; Middle Aged; Myocardial Ischemia - therapy; Myocardium - pathology; Phenotype; Prospective Studies; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left - therapy; stem cell; coronary artery bypass; mesenchymal stromal cells