Biomarkers in acute medicine

Abstract Biomarkers represent a major technological innovation in medicine. This article discusses the definition and uses of biomarkers, particularly their role in diagnosis, risk stratification and management of disease. It reviews the current roles of the seven most commonly used biomarkers in th...

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Published inMedicine (Abingdon. 1995, UK ed.) Vol. 45; no. 3; pp. 150 - 156
Main Author Vaughan, Louella
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.03.2017
Subjects
Biomarkers
brain natriuretic peptide
C-reactive protein
creatine kinase
d-dimer
diagnosis
Internal Medicine
procalcitonin
risk stratification
troponin
C-reactive protein
risk stratification
troponin
d-dimer
Biomarkers
brain natriuretic peptide
diagnosis
procalcitonin
creatine kinase
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Summary:Abstract Biomarkers represent a major technological innovation in medicine. This article discusses the definition and uses of biomarkers, particularly their role in diagnosis, risk stratification and management of disease. It reviews the current roles of the seven most commonly used biomarkers in the acute setting (troponin, creatine kinase, myoglobin, brain natriuretic peptide, d -dimer, C-reactive protein, procalcitonin). The article looks briefly at the utility of point-of-care testing, which, despite concerns about accuracy, can help to risk-stratify patients more efficiently at the point of presentation. Biomarkers currently in development for diagnosis and prognostication across a spectrum of disease are surveyed.
ISSN:1357-3039
1878-9390
DOI:10.1016/j.mpmed.2016.12.005