Update on the Diagnosis and Treatment of Lumbar Nonunions

Strategies in the diagnosis and treatment of lumbar nonunion were reviewed. The reported rates of lumbar nonunion ranged from 5 to 70% of cases depending on surgical technique. Risk factors include tobacco use, malnutrition, oral anti-inflammatory use, multilevel fusion, prior spine surgery, and sag...

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Published inSeminars in spine surgery Vol. 20; no. 1; pp. 20 - 26
Main Authors Patel, Alpesh A., MD, Spiker, William R., MD
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.03.2008
Subjects
failed fusion
lumbar nonunion
lumbar pseudarthrosis
Orthopedics
pseudarthrosis treatment
lumbar pseudarthrosis
failed fusion
lumbar nonunion
pseudarthrosis treatment
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Abstract Strategies in the diagnosis and treatment of lumbar nonunion were reviewed. The reported rates of lumbar nonunion ranged from 5 to 70% of cases depending on surgical technique. Risk factors include tobacco use, malnutrition, oral anti-inflammatory use, multilevel fusion, prior spine surgery, and sagittal imbalance. Diagnosis can be based on history, examination, and radiographic imaging including reconstructed computed tomography. The surgical approach is guided by prior surgery as well as the sagittal balance of the spine. The use of autologous bone graft as well as biologic graft extenders or substitutes may be of benefit. Lumbar nonunion presents a difficult clinical scenario. Surgical revision yields high fusion rates but may not improve functional outcomes.
AbstractList Strategies in the diagnosis and treatment of lumbar nonunion were reviewed. The reported rates of lumbar nonunion ranged from 5 to 70% of cases depending on surgical technique. Risk factors include tobacco use, malnutrition, oral anti-inflammatory use, multilevel fusion, prior spine surgery, and sagittal imbalance. Diagnosis can be based on history, examination, and radiographic imaging including reconstructed computed tomography. The surgical approach is guided by prior surgery as well as the sagittal balance of the spine. The use of autologous bone graft as well as biologic graft extenders or substitutes may be of benefit. Lumbar nonunion presents a difficult clinical scenario. Surgical revision yields high fusion rates but may not improve functional outcomes.
Author Patel, Alpesh A., MD
Spiker, William R., MD
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CitedBy_id crossref_primary_10_1007_s10143_019_01225_x
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Cites_doi 10.2106/00004623-199173020-00011
10.1097/00007632-198611000-00015
10.2106/00004623-197254060-00006
10.1097/01.brs.0000186470.28070.7b
10.1097/01.brs.0000238968.82799.d9
10.1097/00007632-198903000-00014
10.1097/01.brs.0000190812.08447.ba
10.1007/s00586-006-0147-3
10.1302/0301-620X.62B1.7351437
10.1148/radiology.204.3.9280271
10.1097/00007632-199103001-00025
10.1097/01.brs.0000188294.01845.20
10.2106/00004623-197254040-00006
10.1097/00007632-199511000-00009
10.1097/00007632-199608150-00006
10.1097/00007632-199805150-00015
10.1097/00004728-199007000-00013
10.1007/s005860050007
10.1097/00007632-199811010-00021
10.1016/j.spinee.2005.11.003
10.1097/00007632-199712150-00003
10.1016/S0030-5898(05)70033-X
10.1016/j.spinee.2006.06.381
10.1097/00003086-200408000-00018
10.1097/00003086-200402000-00012
10.1097/00007632-199712010-00009
10.1097/00007632-199512150-00003
10.2106/00004623-198567080-00002
10.1016/j.spinee.2004.05.253
10.2106/00004623-198163020-00013
10.1097/00003086-198503000-00006
10.1097/00007632-199208000-00015
10.1097/00007632-199408150-00008
10.1016/S0030-5898(20)31223-2
10.1097/01.brs.0000162929.19985.d2
10.1097/00007632-199507150-00001
10.1016/S1529-9430(03)00427-3
10.1097/00007632-199911010-00003
10.1097/00007632-200203150-00003
10.1097/00002517-199306060-00001
10.1097/00007632-199404150-00007
10.1097/00007632-199306150-00011
10.1097/00003086-200002000-00006
10.1097/01.bsd.0000211226.97178.b9
10.1097/00007632-200001010-00021
10.1097/00024720-200304000-00001
10.1016/S0030-5898(20)31535-2
10.1097/00007632-200206010-00002
10.1097/00007632-199106001-00017
10.1097/01.BRS.0000109994.36349.D7
10.1126/science.150.3698.893
10.1097/00007632-199307000-00010
10.2106/00004623-200304000-00007
10.1097/01.brs.0000217619.57333.96
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Keywords lumbar pseudarthrosis
failed fusion
lumbar nonunion
pseudarthrosis treatment
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References Toribatake, Hutton, Tomita (bib13) 1998; 23
Silcox, Daftari, Boden (bib17) 1995; 20
Mermer, Gupta, Wheeler (bib33) 2004; 29
Lee, Dorcil, Radomisli (bib4) 2004; 419
Ames, Smith, Preul (bib24) 2005; 30
Albee (bib1) 1911; 57
Glassman, Carreon, Djurasovic (bib62) 2007; 7
Heggeness, Esses, Mody (bib37) 1993; 18
Hilibrand, Dina (bib48) 1998; 29
Bridwell, Sedgewick, O’Brien (bib8) 1993; 6
Watkins, Bragg (bib34) 1956; 102
Hayes, Howard, Gruel (bib40) 1989; 14
Gertzbein, Hollopeter, Hall (bib58) 1998; 23
Vaccaro, Anderson, Patel (bib63) 2005; 30
Kim, Bridwell, Lenke (bib30) 2006; 31
Suda, Ito, Abumi (bib31) 2006; 18
Fischgrund, Mackay, Herkowitz (bib9) 1997; 22
Bosworth (bib35) 1948
Benli, Ates, Akalin (bib39) 2007; 16
Buttermann, Glazer, Hu (bib57) 1997; 22
Lehman, Kuklo, Freedman (bib28) 2004; 4
Sandhu, Toth, Diwan (bib38) 2002; 27
Burkus, Heim, Gormet (bib61) 2003; 16
Mundoz, Garcia-Vallejo, Sempere (bib18) 2004; 13
Cotler, Star (bib32) 1990
Daftari, Whitesides, Heller (bib16) 1994; 19
Huang, Khan, Sandhu (bib26) 2005; 30
Urist (bib60) 1965; 150
Riew, Long, Rhee (bib19) 2003; 85
Xue, Li, Zou (bib27) 2005; 30
Stauffer, Coventry (bib6) 1972; 54
Sawin, Dickman, Crawford (bib22) 2001; 94
Cohen, Chotivichit, Fujita (bib56) 2000; 371
Swank, Lonstein, Moe (bib5) 1981; 63
Rothman, Booth (bib14) 1975; 6
Kant, Daum, Dean (bib44) 1995; 20
(bib3) 1992
Thalgott, LaRocca, Gardner (bib53) 1991; 16
Boden, Schimandle, Hutton (bib12) 1995; 20
Martin, Boden, Titus (bib20) 1999; 24
Brown, Orme, Richardson (bib15) 1986; 11
McMaster, Merrick (bib47) 1980; 62
Hannon, Wetta (bib36) 1977; 123
Albert, Pinto, Denis (bib59) 2000; 25
Pateder, Park, Kebaish (bib29) 2006; 31
Cassinelli, Wallach, Hanscom (bib54) 2006; 6
Zinreich, Ung, Davis (bib46) 1990; 14
Brodsky, Kovalsky, Khalil (bib42) 1991; 16
Becker (bib2) 2003; 33
Stauffer, Coventry (bib7) 1972; 54
Brantigan, Neidro, Toohey (bib10) 2004; 4
Lauerman, Bradford, Transfeldt (bib51) 1991; 73
Sama, Khan, Myers (bib25) 2004; 425
Blumenthal, Gill (bib41) 1993; 18
Kim, Michelsen (bib52) 1992; 17
Dawson, Clader, Bassett (bib43) 1985; 67
Djukic, Lang, Morris, Hoaglund (bib50) 1990; 21
Freeman, Licina, Mehdian (bib55) 2000; 9
Bouchard, Koka, Bensusan (bib23) 1994; 19
Rothman, Glenn (bib45) 1985; 193
Dimar, Ante, Zhang (bib21) 1996; 21
Jacobson, Starok, Pathria (bib49) 1997; 204
Fritzell, Hagg, Wessberg (bib11) 2002; 27
Freeman (10.1053/j.semss.2007.11.004_bib55) 2000; 9
Brown (10.1053/j.semss.2007.11.004_bib15) 1986; 11
Thalgott (10.1053/j.semss.2007.11.004_bib53) 1991; 16
Rothman (10.1053/j.semss.2007.11.004_bib14) 1975; 6
Glassman (10.1053/j.semss.2007.11.004_bib62) 2007; 7
Xue (10.1053/j.semss.2007.11.004_bib27) 2005; 30
Lehman (10.1053/j.semss.2007.11.004_bib28) 2004; 4
Bouchard (10.1053/j.semss.2007.11.004_bib23) 1994; 19
Blumenthal (10.1053/j.semss.2007.11.004_bib41) 1993; 18
Swank (10.1053/j.semss.2007.11.004_bib5) 1981; 63
Sandhu (10.1053/j.semss.2007.11.004_bib38) 2002; 27
Cassinelli (10.1053/j.semss.2007.11.004_bib54) 2006; 6
Stauffer (10.1053/j.semss.2007.11.004_bib7) 1972; 54
Bridwell (10.1053/j.semss.2007.11.004_bib8) 1993; 6
Mundoz (10.1053/j.semss.2007.11.004_bib18) 2004; 13
Hannon (10.1053/j.semss.2007.11.004_bib36) 1977; 123
Kant (10.1053/j.semss.2007.11.004_bib44) 1995; 20
Suda (10.1053/j.semss.2007.11.004_bib31) 2006; 18
Urist (10.1053/j.semss.2007.11.004_bib60) 1965; 150
Kim (10.1053/j.semss.2007.11.004_bib52) 1992; 17
Kim (10.1053/j.semss.2007.11.004_bib30) 2006; 31
Martin (10.1053/j.semss.2007.11.004_bib20) 1999; 24
Silcox (10.1053/j.semss.2007.11.004_bib17) 1995; 20
Sawin (10.1053/j.semss.2007.11.004_bib22) 2001; 94
Heggeness (10.1053/j.semss.2007.11.004_bib37) 1993; 18
Mermer (10.1053/j.semss.2007.11.004_bib33) 2004; 29
Cotler (10.1053/j.semss.2007.11.004_bib32) 1990
Jacobson (10.1053/j.semss.2007.11.004_bib49) 1997; 204
Fischgrund (10.1053/j.semss.2007.11.004_bib9) 1997; 22
Zinreich (10.1053/j.semss.2007.11.004_bib46) 1990; 14
Toribatake (10.1053/j.semss.2007.11.004_bib13) 1998; 23
Watkins (10.1053/j.semss.2007.11.004_bib34) 1956; 102
Boden (10.1053/j.semss.2007.11.004_bib12) 1995; 20
Huang (10.1053/j.semss.2007.11.004_bib26) 2005; 30
Vaccaro (10.1053/j.semss.2007.11.004_bib63) 2005; 30
Burkus (10.1053/j.semss.2007.11.004_bib61) 2003; 16
Albert (10.1053/j.semss.2007.11.004_bib59) 2000; 25
Stauffer (10.1053/j.semss.2007.11.004_bib6) 1972; 54
Bosworth (10.1053/j.semss.2007.11.004_bib35) 1948
Benli (10.1053/j.semss.2007.11.004_bib39) 2007; 16
(10.1053/j.semss.2007.11.004_bib3) 1992
Daftari (10.1053/j.semss.2007.11.004_bib16) 1994; 19
Riew (10.1053/j.semss.2007.11.004_bib19) 2003; 85
McMaster (10.1053/j.semss.2007.11.004_bib47) 1980; 62
Hilibrand (10.1053/j.semss.2007.11.004_bib48) 1998; 29
Gertzbein (10.1053/j.semss.2007.11.004_bib58) 1998; 23
Pateder (10.1053/j.semss.2007.11.004_bib29) 2006; 31
Rothman (10.1053/j.semss.2007.11.004_bib45) 1985; 193
Lauerman (10.1053/j.semss.2007.11.004_bib51) 1991; 73
Cohen (10.1053/j.semss.2007.11.004_bib56) 2000; 371
Sama (10.1053/j.semss.2007.11.004_bib25) 2004; 425
Buttermann (10.1053/j.semss.2007.11.004_bib57) 1997; 22
Lee (10.1053/j.semss.2007.11.004_bib4) 2004; 419
Becker (10.1053/j.semss.2007.11.004_bib2) 2003; 33
Djukic (10.1053/j.semss.2007.11.004_bib50) 1990; 21
Brantigan (10.1053/j.semss.2007.11.004_bib10) 2004; 4
Brodsky (10.1053/j.semss.2007.11.004_bib42) 1991; 16
Dawson (10.1053/j.semss.2007.11.004_bib43) 1985; 67
Fritzell (10.1053/j.semss.2007.11.004_bib11) 2002; 27
Albee (10.1053/j.semss.2007.11.004_bib1) 1911; 57
Dimar (10.1053/j.semss.2007.11.004_bib21) 1996; 21
Ames (10.1053/j.semss.2007.11.004_bib24) 2005; 30
Hayes (10.1053/j.semss.2007.11.004_bib40) 1989; 14
References_xml – volume: 193
  start-page: 47
  year: 1985
  end-page: 56
  ident: bib45
  article-title: CT evaluation of interbody fusion
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Glenn
– volume: 22
  start-page: 2807
  year: 1997
  end-page: 2812
  ident: bib9
  article-title: 1997 Volvo Award winner in clinical studies
  publication-title: Spine
  contributor:
    fullname: Herkowitz
– volume: 30
  start-page: 2709
  year: 2005
  end-page: 2716
  ident: bib63
  article-title: Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study
  publication-title: Spine
  contributor:
    fullname: Patel
– volume: 13
  start-page: 367
  year: 2004
  end-page: 373
  ident: bib18
  article-title: Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidine
  publication-title: Eur Spine J
  contributor:
    fullname: Sempere
– volume: 21
  start-page: 1870
  year: 1996
  end-page: 1876
  ident: bib21
  article-title: The effects of nonsteriodal anti-inflammatory drugs on posterior spinal fusion in the rat
  publication-title: Spine
  contributor:
    fullname: Zhang
– volume: 11
  start-page: 942
  year: 1986
  end-page: 943
  ident: bib15
  article-title: The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study
  publication-title: Spine
  contributor:
    fullname: Richardson
– volume: 54
  start-page: 756
  year: 1972
  end-page: 768
  ident: bib6
  article-title: Anterior interbody lumbar spine fusion
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Coventry
– volume: 4
  start-page: 36
  year: 2004
  end-page: 43
  ident: bib28
  article-title: The effect of alendronate sodium on spinal fusion: a rat model
  publication-title: Spine J
  contributor:
    fullname: Freedman
– volume: 23
  start-page: 1149
  year: 1998
  end-page: 1154
  ident: bib13
  article-title: Vascularization of the fusion mass in a posterolateral intertransverse process fusion
  publication-title: Spine
  contributor:
    fullname: Tomita
– volume: 31
  start-page: E314
  year: 2006
  end-page: E319
  ident: bib29
  article-title: Spinal fusion after revision surgery for pseudarthrosis in adult scoliosis
  publication-title: Spine
  contributor:
    fullname: Kebaish
– volume: 24
  start-page: 2188
  year: 1999
  end-page: 2193
  ident: bib20
  article-title: Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketolorac, a nonsteriodal antiinflammatory drug (NSAID), on posterolateral lumbar intertransverse process spinal fusion
  publication-title: Spine
  contributor:
    fullname: Titus
– volume: 29
  start-page: 591
  year: 1998
  end-page: 601
  ident: bib48
  article-title: The use of diagnostic imaging to assess spinal arthrodesis
  publication-title: Orthop Clin North Am
  contributor:
    fullname: Dina
– volume: 54
  start-page: 1195
  year: 1972
  end-page: 1204
  ident: bib7
  article-title: Posterolateral lumbar spine fusion
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Coventry
– volume: 204
  start-page: 853
  year: 1997
  end-page: 858
  ident: bib49
  article-title: Pseudarthrosis: US evaluation after posterolateral spinal fusion: work in progress
  publication-title: Radiology
  contributor:
    fullname: Pathria
– volume: 73
  start-page: 222
  year: 1991
  end-page: 236
  ident: bib51
  article-title: Management of pseudarthrosis after arthrodesis of the spine for idiopathic scoliosis
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Transfeldt
– volume: 4
  start-page: 681
  year: 2004
  end-page: 688
  ident: bib10
  article-title: The lumbar I/F cage for posterior lumbar interbody fusion with the variable screw placement system: 10 year results of a Food and Drug Administration clinical trial
  publication-title: Spine J
  contributor:
    fullname: Toohey
– volume: 27
  year: 2002
  ident: bib38
  article-title: Histological evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusion
  publication-title: Spine
  contributor:
    fullname: Diwan
– volume: 25
  start-page: 123
  year: 2000
  end-page: 129
  ident: bib59
  article-title: Management of symptomatic lumbar pseudarthrosis with anteroposterior fusion
  publication-title: Spine
  contributor:
    fullname: Denis
– volume: 16
  start-page: S170
  year: 1991
  end-page: S175
  ident: bib53
  article-title: Reconstruction of failed lumbar surgery with narrow AO DCP plates for spinal arthrodesis
  publication-title: Spine
  contributor:
    fullname: Gardner
– volume: 22
  start-page: 2748
  year: 1997
  end-page: 2755
  ident: bib57
  article-title: Revision of failed lumbar fusions
  publication-title: Spine
  contributor:
    fullname: Hu
– volume: 67
  start-page: 1153
  year: 1985
  end-page: 1159
  ident: bib43
  article-title: A comparison of different methods used to diagnose pseudarthrosis following posterior spinal fusion for scoliosis
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Bassett
– volume: 150
  start-page: 893
  year: 1965
  end-page: 899
  ident: bib60
  article-title: Bone: formation by autoinduction
  publication-title: Science
  contributor:
    fullname: Urist
– volume: 62
  start-page: 65
  year: 1980
  end-page: 72
  ident: bib47
  article-title: The scintigraphic assessment of the scoliotic spine after fusion
  publication-title: J Bone Joint Surg Br
  contributor:
    fullname: Merrick
– volume: 18
  start-page: 1186
  year: 1993
  end-page: 1189
  ident: bib41
  article-title: Can lumbar spine radiographs accurately determine fusion in postoperative patients?
  publication-title: Spine
  contributor:
    fullname: Gill
– volume: 29
  start-page: 249
  year: 2004
  end-page: 256
  ident: bib33
  article-title: Efficacy of osteogenic protein-1 in a challenging multilevel fusion model
  publication-title: Spine
  contributor:
    fullname: Wheeler
– volume: 371
  start-page: 46
  year: 2000
  end-page: 55
  ident: bib56
  article-title: Pseudarthrosis repair: autogenous iliac crest versus femoral ring allograft
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Fujita
– volume: 57
  start-page: 885
  year: 1911
  end-page: 886
  ident: bib1
  article-title: Transplantation of a portion of the tibia into the spine for Pott’s disease
  publication-title: J Bone Joint Surg
  contributor:
    fullname: Albee
– volume: 6
  start-page: 299
  year: 1975
  end-page: 304
  ident: bib14
  article-title: Failures of spinal fusion
  publication-title: Orthop Clin North Am
  contributor:
    fullname: Booth
– volume: 94
  start-page: 76
  year: 2001
  end-page: 81
  ident: bib22
  article-title: The effects of dexamethasone on bone fusion in an experimental model of posterolateral lumbar spinal arthrodesis
  publication-title: J Neurosurg
  contributor:
    fullname: Crawford
– volume: 31
  start-page: 2329
  year: 2006
  end-page: 2336
  ident: bib30
  article-title: Pseudarthrosis in long adult spinal deformity instrumentation and fusion to the sacrum: prevalance and risk factor analysis in 144 cases
  publication-title: Spine
  contributor:
    fullname: Lenke
– volume: 63
  start-page: 268
  year: 1981
  end-page: 287
  ident: bib5
  article-title: Surgical treatment of adult scoliosis
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Moe
– volume: 14
  start-page: 574
  year: 1990
  ident: bib46
  article-title: Three-dimensional CT imaging in postsurgical “failed back” syndrome
  publication-title: J Comp Assisted Tomogr
  contributor:
    fullname: Davis
– volume: 425
  start-page: 135
  year: 2004
  end-page: 142
  ident: bib25
  article-title: High dose alendronate uncouples osteoclast and osteoblast function: a study in a rat spine pseudarthrosis model
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Myers
– volume: 30
  start-page: 2585
  year: 2005
  end-page: 2592
  ident: bib24
  article-title: Effect of recombinant human bone morphogenetic protein-2 in an experimental model of spinal fusion in a radiated area
  publication-title: Spine
  contributor:
    fullname: Preul
– volume: 27
  start-page: 1131
  year: 2002
  end-page: 1141
  ident: bib11
  article-title: Chronic low back pain and fusion: a comparison of three surgical techniques: A prospective multicenter randomized study from the Swedish Lumbar Spine Study Group
  publication-title: Spine
  contributor:
    fullname: Wessberg
– volume: 20
  start-page: 2626
  year: 1995
  end-page: 2632
  ident: bib12
  article-title: 1995 Volvo Award in basic sciences
  publication-title: Spine
  contributor:
    fullname: Hutton
– volume: 16
  start-page: 113
  year: 2003
  end-page: 122
  ident: bib61
  article-title: Is Infuse bone graft superior to autograft bone?
  publication-title: J Spinal Disord Tech
  contributor:
    fullname: Gormet
– volume: 17
  start-page: 957
  year: 1992
  end-page: 960
  ident: bib52
  article-title: Revision surgery for failed back syndrome
  publication-title: Spine
  contributor:
    fullname: Michelsen
– volume: 16
  start-page: S261
  year: 1991
  end-page: S265
  ident: bib42
  article-title: Correlation of radiologic assessment of lumbar spine fusions with surgical exploration
  publication-title: Spine
  contributor:
    fullname: Khalil
– volume: 14
  start-page: 327
  year: 1989
  end-page: 331
  ident: bib40
  article-title: Roentgenographic evaluation of lumbar spine flexion-extension in asymptomatic individuals
  publication-title: Spine
  contributor:
    fullname: Gruel
– year: 1992
  ident: bib3
  publication-title: Campbell’s Operative Orthopaedics: Nonunion and Malunion
– volume: 20
  start-page: 2313
  year: 1995
  end-page: 2317
  ident: bib44
  article-title: Evaluation of lumbar spine fusion
  publication-title: Spine
  contributor:
    fullname: Dean
– volume: 19
  start-page: 1836
  year: 1994
  end-page: 1841
  ident: bib23
  article-title: Effects of irradiation on posterior spinal fusions: a rabbit model
  publication-title: Spine
  contributor:
    fullname: Bensusan
– volume: 7
  start-page: 44
  year: 2007
  end-page: 49
  ident: bib62
  article-title: Posterolateral lumbar spine fusion with infuse bone graft
  publication-title: Spine J
  contributor:
    fullname: Djurasovic
– volume: 123
  start-page: 42
  year: 1977
  end-page: 44
  ident: bib36
  article-title: Failure of technetium bone scanning to detect pseudarthroses in spinal fusion for scoliosis
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Wetta
– volume: 21
  start-page: 603
  year: 1990
  end-page: 624
  ident: bib50
  article-title: The postoperative spine—magnetic resonance imaging
  publication-title: Orthop Clin North Am
  contributor:
    fullname: Hoaglund
– volume: 419
  start-page: 71
  year: 2004
  end-page: 75
  ident: bib4
  article-title: Nonunion of the spine: a review
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Radomisli
– volume: 30
  start-page: 1116
  year: 2005
  end-page: 1121
  ident: bib27
  article-title: The influence of alendronate treatment and bone graft volume on posterior lateral spine fusion in a porcine model
  publication-title: Spine J
  contributor:
    fullname: Zou
– volume: 33
  start-page: 30
  year: 2003
  end-page: 32
  ident: bib2
  article-title: Spine-tingling prospects: artificial disk implants are among the new technologies expected to revolutionize the outcomes of back surgery
  publication-title: Mod Healthcare
  contributor:
    fullname: Becker
– start-page: 361
  year: 1990
  end-page: 387
  ident: bib32
  article-title: Complications of spinal fusion
  publication-title: Spinal Fusion: Science and Technique
  contributor:
    fullname: Star
– volume: 19
  start-page: 904
  year: 1994
  end-page: 911
  ident: bib16
  article-title: Nicotine on the revascularization of bone graft
  publication-title: Spine
  contributor:
    fullname: Heller
– volume: 102
  start-page: 604
  year: 1956
  end-page: 606
  ident: bib34
  article-title: Lumbosacral fusion: results with early ambulation
  publication-title: Surg Gynecol Obstet
  contributor:
    fullname: Bragg
– volume: 23
  start-page: 2352
  year: 1998
  end-page: 2356
  ident: bib58
  article-title: Pseudarthrosis of the lumbar spine
  publication-title: Spine
  contributor:
    fullname: Hall
– volume: 30
  start-page: 2516
  year: 2005
  end-page: 2522
  ident: bib26
  article-title: Alendronate inhibits spine fusion in a rat model
  publication-title: Spine
  contributor:
    fullname: Sandhu
– year: 1948
  ident: bib35
  article-title: Technique of spina fusion: Pseudarthrosis and method of repair
  publication-title: AAOS Instructional Course Lectures
  contributor:
    fullname: Bosworth
– volume: 18
  start-page: 1016
  year: 1993
  end-page: 1020
  ident: bib37
  article-title: A histological study of lumbar pseudarthrosis
  publication-title: Spine
  contributor:
    fullname: Mody
– volume: 9
  start-page: 42
  year: 2000
  end-page: 46
  ident: bib55
  article-title: Posterior lumbar interbody fusion combined with posterolateral fusion: 5 year results in 60 patients
  publication-title: Eur Spine J
  contributor:
    fullname: Mehdian
– volume: 6
  start-page: 461
  year: 1993
  end-page: 472
  ident: bib8
  article-title: The role of fusion and instrumentation in the treatment of degenerative spondylolisthesis with spinal stenosis
  publication-title: J Spinal Disord Tech
  contributor:
    fullname: O’Brien
– volume: 20
  start-page: 1549
  year: 1995
  end-page: 1553
  ident: bib17
  article-title: The effect of nicotine on spinal fusion
  publication-title: Spine
  contributor:
    fullname: Boden
– volume: 16
  start-page: 381
  year: 2007
  end-page: 391
  ident: bib39
  article-title: Miniumum 10 years follow-up surgical results of adolescent idiopathic scoliosis patients treated with TSRH instrumentation
  publication-title: Eur Spine J
  contributor:
    fullname: Akalin
– volume: 85
  start-page: 632
  year: 2003
  end-page: 634
  ident: bib19
  article-title: Time-dependent inhibitory effects of indomethicin on spinal fusion
  publication-title: J Bone Joint Surg Am
  contributor:
    fullname: Rhee
– volume: 18
  start-page: 541
  year: 2006
  end-page: 546
  ident: bib31
  article-title: Radiological risk factors of pseudarthrosis and/or instrument breakage after PLF with pedicle screw system in isthmic spondylolisthesis
  publication-title: J Spinal Disord Tech
  contributor:
    fullname: Abumi
– volume: 6
  start-page: 428
  year: 2006
  end-page: 434
  ident: bib54
  article-title: Prospective clinical outcomes of revision fusion surgery in patients with pseudarthrosis after posterior lumbar interbody fusions using stand-alone metallic cages
  publication-title: Spine J
  contributor:
    fullname: Hanscom
– volume: 73
  start-page: 222
  year: 1991
  ident: 10.1053/j.semss.2007.11.004_bib51
  article-title: Management of pseudarthrosis after arthrodesis of the spine for idiopathic scoliosis
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-199173020-00011
  contributor:
    fullname: Lauerman
– volume: 11
  start-page: 942
  year: 1986
  ident: 10.1053/j.semss.2007.11.004_bib15
  article-title: The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study
  publication-title: Spine
  doi: 10.1097/00007632-198611000-00015
  contributor:
    fullname: Brown
– volume: 54
  start-page: 1195
  year: 1972
  ident: 10.1053/j.semss.2007.11.004_bib7
  article-title: Posterolateral lumbar spine fusion
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-197254060-00006
  contributor:
    fullname: Stauffer
– volume: 30
  start-page: 2516
  year: 2005
  ident: 10.1053/j.semss.2007.11.004_bib26
  article-title: Alendronate inhibits spine fusion in a rat model
  publication-title: Spine
  doi: 10.1097/01.brs.0000186470.28070.7b
  contributor:
    fullname: Huang
– volume: 31
  start-page: 2329
  year: 2006
  ident: 10.1053/j.semss.2007.11.004_bib30
  article-title: Pseudarthrosis in long adult spinal deformity instrumentation and fusion to the sacrum: prevalance and risk factor analysis in 144 cases
  publication-title: Spine
  doi: 10.1097/01.brs.0000238968.82799.d9
  contributor:
    fullname: Kim
– volume: 102
  start-page: 604
  year: 1956
  ident: 10.1053/j.semss.2007.11.004_bib34
  article-title: Lumbosacral fusion: results with early ambulation
  publication-title: Surg Gynecol Obstet
  contributor:
    fullname: Watkins
– volume: 14
  start-page: 327
  year: 1989
  ident: 10.1053/j.semss.2007.11.004_bib40
  article-title: Roentgenographic evaluation of lumbar spine flexion-extension in asymptomatic individuals
  publication-title: Spine
  doi: 10.1097/00007632-198903000-00014
  contributor:
    fullname: Hayes
– volume: 57
  start-page: 885
  year: 1911
  ident: 10.1053/j.semss.2007.11.004_bib1
  article-title: Transplantation of a portion of the tibia into the spine for Pott’s disease
  publication-title: J Bone Joint Surg
  contributor:
    fullname: Albee
– volume: 30
  start-page: 2709
  year: 2005
  ident: 10.1053/j.semss.2007.11.004_bib63
  article-title: Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study
  publication-title: Spine
  doi: 10.1097/01.brs.0000190812.08447.ba
  contributor:
    fullname: Vaccaro
– volume: 16
  start-page: 381
  year: 2007
  ident: 10.1053/j.semss.2007.11.004_bib39
  article-title: Miniumum 10 years follow-up surgical results of adolescent idiopathic scoliosis patients treated with TSRH instrumentation
  publication-title: Eur Spine J
  doi: 10.1007/s00586-006-0147-3
  contributor:
    fullname: Benli
– volume: 62
  start-page: 65
  year: 1980
  ident: 10.1053/j.semss.2007.11.004_bib47
  article-title: The scintigraphic assessment of the scoliotic spine after fusion
  publication-title: J Bone Joint Surg Br
  doi: 10.1302/0301-620X.62B1.7351437
  contributor:
    fullname: McMaster
– volume: 204
  start-page: 853
  year: 1997
  ident: 10.1053/j.semss.2007.11.004_bib49
  article-title: Pseudarthrosis: US evaluation after posterolateral spinal fusion: work in progress
  publication-title: Radiology
  doi: 10.1148/radiology.204.3.9280271
  contributor:
    fullname: Jacobson
– volume: 16
  start-page: S170
  issue: suppl
  year: 1991
  ident: 10.1053/j.semss.2007.11.004_bib53
  article-title: Reconstruction of failed lumbar surgery with narrow AO DCP plates for spinal arthrodesis
  publication-title: Spine
  doi: 10.1097/00007632-199103001-00025
  contributor:
    fullname: Thalgott
– volume: 30
  start-page: 2585
  year: 2005
  ident: 10.1053/j.semss.2007.11.004_bib24
  article-title: Effect of recombinant human bone morphogenetic protein-2 in an experimental model of spinal fusion in a radiated area
  publication-title: Spine
  doi: 10.1097/01.brs.0000188294.01845.20
  contributor:
    fullname: Ames
– volume: 54
  start-page: 756
  year: 1972
  ident: 10.1053/j.semss.2007.11.004_bib6
  article-title: Anterior interbody lumbar spine fusion
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-197254040-00006
  contributor:
    fullname: Stauffer
– year: 1992
  ident: 10.1053/j.semss.2007.11.004_bib3
– volume: 20
  start-page: 2313
  year: 1995
  ident: 10.1053/j.semss.2007.11.004_bib44
  article-title: Evaluation of lumbar spine fusion
  publication-title: Spine
  doi: 10.1097/00007632-199511000-00009
  contributor:
    fullname: Kant
– volume: 21
  start-page: 1870
  year: 1996
  ident: 10.1053/j.semss.2007.11.004_bib21
  article-title: The effects of nonsteriodal anti-inflammatory drugs on posterior spinal fusion in the rat
  publication-title: Spine
  doi: 10.1097/00007632-199608150-00006
  contributor:
    fullname: Dimar
– volume: 23
  start-page: 1149
  year: 1998
  ident: 10.1053/j.semss.2007.11.004_bib13
  article-title: Vascularization of the fusion mass in a posterolateral intertransverse process fusion
  publication-title: Spine
  doi: 10.1097/00007632-199805150-00015
  contributor:
    fullname: Toribatake
– volume: 14
  start-page: 574
  year: 1990
  ident: 10.1053/j.semss.2007.11.004_bib46
  article-title: Three-dimensional CT imaging in postsurgical “failed back” syndrome
  publication-title: J Comp Assisted Tomogr
  doi: 10.1097/00004728-199007000-00013
  contributor:
    fullname: Zinreich
– volume: 9
  start-page: 42
  year: 2000
  ident: 10.1053/j.semss.2007.11.004_bib55
  article-title: Posterior lumbar interbody fusion combined with posterolateral fusion: 5 year results in 60 patients
  publication-title: Eur Spine J
  doi: 10.1007/s005860050007
  contributor:
    fullname: Freeman
– volume: 23
  start-page: 2352
  year: 1998
  ident: 10.1053/j.semss.2007.11.004_bib58
  article-title: Pseudarthrosis of the lumbar spine
  publication-title: Spine
  doi: 10.1097/00007632-199811010-00021
  contributor:
    fullname: Gertzbein
– volume: 6
  start-page: 428
  year: 2006
  ident: 10.1053/j.semss.2007.11.004_bib54
  article-title: Prospective clinical outcomes of revision fusion surgery in patients with pseudarthrosis after posterior lumbar interbody fusions using stand-alone metallic cages
  publication-title: Spine J
  doi: 10.1016/j.spinee.2005.11.003
  contributor:
    fullname: Cassinelli
– volume: 22
  start-page: 2807
  year: 1997
  ident: 10.1053/j.semss.2007.11.004_bib9
  article-title: 1997 Volvo Award winner in clinical studies
  publication-title: Spine
  doi: 10.1097/00007632-199712150-00003
  contributor:
    fullname: Fischgrund
– volume: 29
  start-page: 591
  year: 1998
  ident: 10.1053/j.semss.2007.11.004_bib48
  article-title: The use of diagnostic imaging to assess spinal arthrodesis
  publication-title: Orthop Clin North Am
  doi: 10.1016/S0030-5898(05)70033-X
  contributor:
    fullname: Hilibrand
– volume: 7
  start-page: 44
  year: 2007
  ident: 10.1053/j.semss.2007.11.004_bib62
  article-title: Posterolateral lumbar spine fusion with infuse bone graft
  publication-title: Spine J
  doi: 10.1016/j.spinee.2006.06.381
  contributor:
    fullname: Glassman
– year: 1948
  ident: 10.1053/j.semss.2007.11.004_bib35
  article-title: Technique of spina fusion: Pseudarthrosis and method of repair
  contributor:
    fullname: Bosworth
– volume: 425
  start-page: 135
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib25
  article-title: High dose alendronate uncouples osteoclast and osteoblast function: a study in a rat spine pseudarthrosis model
  publication-title: Clin Orthop Relat Res
  doi: 10.1097/00003086-200408000-00018
  contributor:
    fullname: Sama
– volume: 419
  start-page: 71
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib4
  article-title: Nonunion of the spine: a review
  publication-title: Clin Orthop Relat Res
  doi: 10.1097/00003086-200402000-00012
  contributor:
    fullname: Lee
– volume: 22
  start-page: 2748
  year: 1997
  ident: 10.1053/j.semss.2007.11.004_bib57
  article-title: Revision of failed lumbar fusions
  publication-title: Spine
  doi: 10.1097/00007632-199712010-00009
  contributor:
    fullname: Buttermann
– volume: 20
  start-page: 2626
  year: 1995
  ident: 10.1053/j.semss.2007.11.004_bib12
  article-title: 1995 Volvo Award in basic sciences
  publication-title: Spine
  doi: 10.1097/00007632-199512150-00003
  contributor:
    fullname: Boden
– volume: 33
  start-page: 30
  year: 2003
  ident: 10.1053/j.semss.2007.11.004_bib2
  article-title: Spine-tingling prospects: artificial disk implants are among the new technologies expected to revolutionize the outcomes of back surgery
  publication-title: Mod Healthcare
  contributor:
    fullname: Becker
– volume: 67
  start-page: 1153
  year: 1985
  ident: 10.1053/j.semss.2007.11.004_bib43
  article-title: A comparison of different methods used to diagnose pseudarthrosis following posterior spinal fusion for scoliosis
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-198567080-00002
  contributor:
    fullname: Dawson
– volume: 4
  start-page: 681
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib10
  article-title: The lumbar I/F cage for posterior lumbar interbody fusion with the variable screw placement system: 10 year results of a Food and Drug Administration clinical trial
  publication-title: Spine J
  doi: 10.1016/j.spinee.2004.05.253
  contributor:
    fullname: Brantigan
– volume: 63
  start-page: 268
  year: 1981
  ident: 10.1053/j.semss.2007.11.004_bib5
  article-title: Surgical treatment of adult scoliosis
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-198163020-00013
  contributor:
    fullname: Swank
– volume: 193
  start-page: 47
  year: 1985
  ident: 10.1053/j.semss.2007.11.004_bib45
  article-title: CT evaluation of interbody fusion
  publication-title: Clin Orthop Relat Res
  doi: 10.1097/00003086-198503000-00006
  contributor:
    fullname: Rothman
– volume: 17
  start-page: 957
  year: 1992
  ident: 10.1053/j.semss.2007.11.004_bib52
  article-title: Revision surgery for failed back syndrome
  publication-title: Spine
  doi: 10.1097/00007632-199208000-00015
  contributor:
    fullname: Kim
– volume: 19
  start-page: 1836
  year: 1994
  ident: 10.1053/j.semss.2007.11.004_bib23
  article-title: Effects of irradiation on posterior spinal fusions: a rabbit model
  publication-title: Spine
  doi: 10.1097/00007632-199408150-00008
  contributor:
    fullname: Bouchard
– start-page: 361
  year: 1990
  ident: 10.1053/j.semss.2007.11.004_bib32
  article-title: Complications of spinal fusion
  contributor:
    fullname: Cotler
– volume: 6
  start-page: 299
  year: 1975
  ident: 10.1053/j.semss.2007.11.004_bib14
  article-title: Failures of spinal fusion
  publication-title: Orthop Clin North Am
  doi: 10.1016/S0030-5898(20)31223-2
  contributor:
    fullname: Rothman
– volume: 30
  start-page: 1116
  year: 2005
  ident: 10.1053/j.semss.2007.11.004_bib27
  article-title: The influence of alendronate treatment and bone graft volume on posterior lateral spine fusion in a porcine model
  publication-title: Spine J
  doi: 10.1097/01.brs.0000162929.19985.d2
  contributor:
    fullname: Xue
– volume: 20
  start-page: 1549
  year: 1995
  ident: 10.1053/j.semss.2007.11.004_bib17
  article-title: The effect of nicotine on spinal fusion
  publication-title: Spine
  doi: 10.1097/00007632-199507150-00001
  contributor:
    fullname: Silcox
– volume: 4
  start-page: 36
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib28
  article-title: The effect of alendronate sodium on spinal fusion: a rat model
  publication-title: Spine J
  doi: 10.1016/S1529-9430(03)00427-3
  contributor:
    fullname: Lehman
– volume: 24
  start-page: 2188
  year: 1999
  ident: 10.1053/j.semss.2007.11.004_bib20
  article-title: Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketolorac, a nonsteriodal antiinflammatory drug (NSAID), on posterolateral lumbar intertransverse process spinal fusion
  publication-title: Spine
  doi: 10.1097/00007632-199911010-00003
  contributor:
    fullname: Martin
– volume: 27
  year: 2002
  ident: 10.1053/j.semss.2007.11.004_bib38
  article-title: Histological evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusion
  publication-title: Spine
  doi: 10.1097/00007632-200203150-00003
  contributor:
    fullname: Sandhu
– volume: 6
  start-page: 461
  year: 1993
  ident: 10.1053/j.semss.2007.11.004_bib8
  article-title: The role of fusion and instrumentation in the treatment of degenerative spondylolisthesis with spinal stenosis
  publication-title: J Spinal Disord Tech
  doi: 10.1097/00002517-199306060-00001
  contributor:
    fullname: Bridwell
– volume: 19
  start-page: 904
  year: 1994
  ident: 10.1053/j.semss.2007.11.004_bib16
  article-title: Nicotine on the revascularization of bone graft
  publication-title: Spine
  doi: 10.1097/00007632-199404150-00007
  contributor:
    fullname: Daftari
– volume: 18
  start-page: 1016
  year: 1993
  ident: 10.1053/j.semss.2007.11.004_bib37
  article-title: A histological study of lumbar pseudarthrosis
  publication-title: Spine
  doi: 10.1097/00007632-199306150-00011
  contributor:
    fullname: Heggeness
– volume: 123
  start-page: 42
  year: 1977
  ident: 10.1053/j.semss.2007.11.004_bib36
  article-title: Failure of technetium bone scanning to detect pseudarthroses in spinal fusion for scoliosis
  publication-title: Clin Orthop Relat Res
  contributor:
    fullname: Hannon
– volume: 371
  start-page: 46
  year: 2000
  ident: 10.1053/j.semss.2007.11.004_bib56
  article-title: Pseudarthrosis repair: autogenous iliac crest versus femoral ring allograft
  publication-title: Clin Orthop Relat Res
  doi: 10.1097/00003086-200002000-00006
  contributor:
    fullname: Cohen
– volume: 18
  start-page: 541
  year: 2006
  ident: 10.1053/j.semss.2007.11.004_bib31
  article-title: Radiological risk factors of pseudarthrosis and/or instrument breakage after PLF with pedicle screw system in isthmic spondylolisthesis
  publication-title: J Spinal Disord Tech
  doi: 10.1097/01.bsd.0000211226.97178.b9
  contributor:
    fullname: Suda
– volume: 25
  start-page: 123
  year: 2000
  ident: 10.1053/j.semss.2007.11.004_bib59
  article-title: Management of symptomatic lumbar pseudarthrosis with anteroposterior fusion
  publication-title: Spine
  doi: 10.1097/00007632-200001010-00021
  contributor:
    fullname: Albert
– volume: 16
  start-page: 113
  year: 2003
  ident: 10.1053/j.semss.2007.11.004_bib61
  article-title: Is Infuse bone graft superior to autograft bone?
  publication-title: J Spinal Disord Tech
  doi: 10.1097/00024720-200304000-00001
  contributor:
    fullname: Burkus
– volume: 21
  start-page: 603
  year: 1990
  ident: 10.1053/j.semss.2007.11.004_bib50
  article-title: The postoperative spine—magnetic resonance imaging
  publication-title: Orthop Clin North Am
  doi: 10.1016/S0030-5898(20)31535-2
  contributor:
    fullname: Djukic
– volume: 27
  start-page: 1131
  year: 2002
  ident: 10.1053/j.semss.2007.11.004_bib11
  article-title: Chronic low back pain and fusion: a comparison of three surgical techniques: A prospective multicenter randomized study from the Swedish Lumbar Spine Study Group
  publication-title: Spine
  doi: 10.1097/00007632-200206010-00002
  contributor:
    fullname: Fritzell
– volume: 16
  start-page: S261
  issue: suppl
  year: 1991
  ident: 10.1053/j.semss.2007.11.004_bib42
  article-title: Correlation of radiologic assessment of lumbar spine fusions with surgical exploration
  publication-title: Spine
  doi: 10.1097/00007632-199106001-00017
  contributor:
    fullname: Brodsky
– volume: 13
  start-page: 367
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib18
  article-title: Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidine
  publication-title: Eur Spine J
  contributor:
    fullname: Mundoz
– volume: 29
  start-page: 249
  year: 2004
  ident: 10.1053/j.semss.2007.11.004_bib33
  article-title: Efficacy of osteogenic protein-1 in a challenging multilevel fusion model
  publication-title: Spine
  doi: 10.1097/01.BRS.0000109994.36349.D7
  contributor:
    fullname: Mermer
– volume: 150
  start-page: 893
  year: 1965
  ident: 10.1053/j.semss.2007.11.004_bib60
  article-title: Bone: formation by autoinduction
  publication-title: Science
  doi: 10.1126/science.150.3698.893
  contributor:
    fullname: Urist
– volume: 94
  start-page: 76
  issue: suppl
  year: 2001
  ident: 10.1053/j.semss.2007.11.004_bib22
  article-title: The effects of dexamethasone on bone fusion in an experimental model of posterolateral lumbar spinal arthrodesis
  publication-title: J Neurosurg
  contributor:
    fullname: Sawin
– volume: 18
  start-page: 1186
  year: 1993
  ident: 10.1053/j.semss.2007.11.004_bib41
  article-title: Can lumbar spine radiographs accurately determine fusion in postoperative patients?
  publication-title: Spine
  doi: 10.1097/00007632-199307000-00010
  contributor:
    fullname: Blumenthal
– volume: 85
  start-page: 632
  year: 2003
  ident: 10.1053/j.semss.2007.11.004_bib19
  article-title: Time-dependent inhibitory effects of indomethicin on spinal fusion
  publication-title: J Bone Joint Surg Am
  doi: 10.2106/00004623-200304000-00007
  contributor:
    fullname: Riew
– volume: 31
  start-page: E314
  year: 2006
  ident: 10.1053/j.semss.2007.11.004_bib29
  article-title: Spinal fusion after revision surgery for pseudarthrosis in adult scoliosis
  publication-title: Spine
  doi: 10.1097/01.brs.0000217619.57333.96
  contributor:
    fullname: Pateder
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Snippet Strategies in the diagnosis and treatment of lumbar nonunion were reviewed. The reported rates of lumbar nonunion ranged from 5 to 70% of cases depending on...
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SubjectTerms failed fusion
lumbar nonunion
lumbar pseudarthrosis
Orthopedics
pseudarthrosis treatment
Title Update on the Diagnosis and Treatment of Lumbar Nonunions
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https://dx.doi.org/10.1053/j.semss.2007.11.004
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