Hepatic microvascular regulatory mechanisms. I. Adrenergic mechanisms

• Published in: Microvascular research Vol. 21; no. 1; pp. 103 - 116
• Main Authors: Reilly, Frank D., McCuskey, Robert S., Cilento, Eugene V.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 1981
• Subjects: Administration, Topical; Animals; Butoxamine - pharmacology; Electric Stimulation; Isoproterenol - administration & dosage; Isoproterenol - pharmacology; Liver - blood supply; Liver - innervation; Male; Microcirculation; Norepinephrine - administration & dosage; Norepinephrine - pharmacology; Practolol - pharmacology; Rats; Receptors, Adrenergic - pharmacology; Receptors, Adrenergic, alpha - pharmacology; Vasoconstriction - drug effects; Venules - drug effects

The neural and pharmacologic responses of the hepatic microvasculature were evaluated in Sprague-Dawley rats anesthetized with urethane or pentobarbital. Various concentrations of several potential vasoactive substances alone or in combination with appropriate blocking agents were administered topic...