A generalized method for matching informational macromolecular code sequences

• Published in: Computers in biology and medicine Vol. 4; no. 1; pp. 43 - 57
• Main Authors: Wong, A.K.C., Reichert, T.A., Cohen, D.N., Aygun, B.O.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.06.1974
• Subjects: Amino Acid Sequence; Animals; Baker's yeast; Base Sequence; Computers; E. coli; Escherichia coli; Information Systems; Macromolecular Substances; Mathematics; Probability; RNA, Transfer; Saccharomyces cerevisiae; Tyrosyl t-RNA; Baker's yeast; Tyrosyl t-RNA; E. coli

The major outlines of an exhaustive algorithm which discovers the optimal correspondence of a pair of code strings from a pre-specified alphabet is presented. The measure of the quality of correspondence is the information required to effect the mutations indicated by the correspondence. This formul...