Autoradiographic distribution of mu and delta opiate receptors in rat brain using highly selective ligands

• Published in: Life sciences (1973) Vol. 33 Suppl 1; p. 227
• Main Authors: Quirion, R, Zajac, J M, Morgat, J L, Roques, B P
• Format: Journal Article
• Language: English
• Published: Netherlands 1983
• Subjects: Animals; Autoradiography; Brain - metabolism; Rats; Receptors, Opioid - metabolism; Receptors, Opioid, delta; Receptors, Opioid, mu; Tissue Distribution; Tritium

We have characterized the autoradiographic distribution of mu and delta opiate receptors in rat brain using [3H]-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol (DAGO) and [3H]D-Thr2, Thr6leu-enkephalin (DTLET), two highly selective ligands for mu and delta opiate receptors, respectively. Both ligands label an apparen...