Intestinal response to 1α,25-dihydroxycholecalciferol I. RNA polymerase, alkaline phosphatase, calcium and phosphorus uptake in vitro, and in vivo calcium transport and accumulation

• Published in: Biochimica et biophysica acta Vol. 538; no. 1; pp. 23 - 33
• Main Authors: Morrissey, Robert L., Zolock, David T., Bikle, Daniel D., Empson, Richard N., Bucci, Thomas J.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 03.01.1978
• Subjects: Alkaline Phosphatase - metabolism; Animals; Bone and Bones - metabolism; Calcium - metabolism; Carrier Proteins - metabolism; Chickens; Dihydroxycholecalciferols - pharmacology; DNA-Directed RNA Polymerases - metabolism; Duodenum - metabolism; Hydroxycholecalciferols - pharmacology; Intestinal Mucosa - metabolism; Male; Phosphorus - metabolism; Rickets - metabolism

The dynamics of intestinal response in rachitic chicks to 1α,25-dihydroxycholecalciferol were evaluated by various biochemical parameters. The following observations were made: 1. 1. The earliest detected intestinal response to 1α,25-dihydroxycholecalciferol was increased in vitro calcium uptake and...