A BRIEF AND MILD METHOD FOR THE GENERATION OF BENZOFURAN-2,3-XYLYLENE IN SOLUTION

• Published in: Synlett no. 9; pp. 627 - 629
• Main Authors: BEDFORD, SB, BEGLEY, MJ, CORNWALL, P, KNIGHT, DW
• Format: Journal Article
• Language: English
• Published: STUTTGART Thieme Medical Publishers 1991
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; ORTHO-XYLYLENE; CYCLOADDITION REACTIONS; FLASH VACUUM PYROLYSIS; STRATEGY; ORTHO-QUINODIMETHANES; 2,3-DIHYDRO-2,3-BIS-(METHYLENE)THIOPHENES; 2,3-DIMETHYLENE-2,3-DIHYDROTHIOPHENE; CHEMISTRY; PHOTOELECTRON-SPECTROSCOPY; ALKALOIDS

Benzofuran-2,3-xylylene 3b (2,3-dimethylene-2,3-dihydrobenzofuran) can be generated at -4-degrees-C in acetonitrile by treatment of 2-acetoxymethyl-3-triisopropylsilymethylbenzofuran (7b), available from 3-methylbenzofuran-2-carboxylic acid dianion (5) in two steps, with tetrabutylammonium fluoride....