The Effect of Albumin and Platelet-Poor Plasma Supplemented Botulinum A Toxin on Bioavaliability: An Experimental Rabbit Model

• Published in: Annals of plastic surgery Vol. 78; no. 4; p. 436
• Main Authors: Sibar, Serhat, Findikcioglu, Kemal, Zinnuroglu, Murat, Cenetoglu, Seyhan
• Format: Journal Article
• Language: English
• Published: United States 01.04.2017
• Subjects: Albumins - pharmacology; Animals; Biological Availability; Botulinum Toxins, Type A - pharmacokinetics; Botulinum Toxins, Type A - pharmacology; Drug Combinations; Ear; Electromyography - methods; Injections, Intramuscular; Male; Models, Animal; Muscle, Skeletal; Muscle, Smooth - drug effects; Platelet Transfusion; Rabbits; Reference Values; Statistics, Nonparametric

Today, botulinum toxin is commonly used for cosmetic purposes throughout the world. Despite various agents reducing the efficiency of toxin are well defined, the studies related to increasing the bioavailability are limited. The purpose of our study is to assess the effect of the preparation of toxi...