Synthesis and NMR characterization of PEGylated β-cyclodextrins

• Published in: Journal of inclusion phenomena and macrocyclic chemistry Vol. 103; no. 5-6; pp. 213 - 222
• Main Authors: Nguyen, Kim Trang Huu, Ba, Yong
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.06.2023; Springer Nature B.V
• Subjects: Biocompatibility; Chemical bonds; Chemical synthesis; Chemistry; Chemistry and Materials Science; Crystallography and Scattering Methods; Cyclodextrins; Food Science; Hydroxyl groups; Inclusion complexes; Industrial applications; Mass spectrometry; MPEG encoders; NMR; Nuclear magnetic resonance; Organic Chemistry; Original Article; Pharmaceuticals; Polyethylene glycol; Two dimensional analysis; Water solubility; PEGylation; 2D NMR; β-cyclodextrin; Inclusion complex; Poly(ethylene glycol)

Cyclodextrins (CDs) and their chemical derivatives are well-known as effective carriers for low-water-soluble molecules for pharmaceutical and other industrial applications. We have carried out the synthesis of PEGylated β-CDs through ether chemical bond linkage between β-CD and poly(ethylene glycol...