Novel multifunctional bioactive glass incorporated alginate/poly(amidoamine) hydrogels with controlled drug release for cartilage tissue regeneration

• Published in: Journal of materials science Vol. 59; no. 4; pp. 1550 - 1569
• Main Authors: Motesadi Zarandi, Fatemeh, Alizadeh, Parvin, Kohoolat, Ghazaleh, Kaviani, Alireza
• Format: Journal Article
• Language: English
• Published: New York Springer US 2024; Springer Nature B.V
• Subjects: Alginates; Biocompatibility; Bioglass; Biological activity; Biomedical materials; Cartilage; Characterization and Evaluation of Materials; Chemistry and Materials Science; Classical Mechanics; Crosslinking; Crystallography and Scattering Methods; Degradation; Hydrogels; Materials for Life Science; Materials for life sciences; Materials Science; Mechanical properties; Modulus of elasticity; Polymer Sciences; Polysaccharides; Regeneration (physiology); Sol-gel processes; Solid Mechanics; Tissue engineering

Tissue engineering faces an intriguing challenge in creating biomaterials for cartilage repair. Within the category of biopolymeric scaffolds, hydrogels made from polysaccharides are particularly suitable for regenerating cartilage tissue. In this paper, a new formulation of biocompatible alginate-b...