Convenient Preparation of Methylthiomethyl p-Tolyl Sulfone Starting from Dimethyl Sulfoxide

• Published in: Bulletin of the Chemical Society of Japan Vol. 56; no. 11; pp. 3543 - 3544
• Main Authors: Ogura, Katsuyuki, Yahata, Nobuhiro, Watanabe, Jun-ichi, Takahashi, Kazumasa, Iida, Hirotada
• Format: Journal Article
• Language: English
• Published: Tokyo The Chemical Society of Japan 01.11.1983; Chemical Society of Japan
• Subjects: Chemistry; Exact sciences and technology; Noncondensed benzenic compounds; Organic chemistry; Preparations and properties; One pot reaction; Thioacetal oxide; Pummerer reaction; Acylal; Sulfoxide; Thioacetal; Organic anhydride; Acetic acid

An efficient method for preparing methylthiomethyl p-tolyl sulfone was accomplished by the Pummerer reaction of dimethyl sulfoxide with acetic anhydride followed by treatment of the resulting acetoxymethyl methyl sulfide with sodium p-toluenesulfinate in the presence of sodium acetate in acetic acid...