MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression - Tabuchi, Tsuyoshi; Satoh, Mamoru; Itoh, Tomonori; Nakamura, Motoyuki (Clinical science (1979), 2012)
Keywords: Aged; Atorvastatin Calcium; Cell Count; Cell Movement - drug effects; Cells, Cultured; Coronary Artery Disease - blood; Coronary Artery Disease - drug therapy; Coronary Artery Disease - genetics; Endothelial Cells - drug effects; Endothelial Cells - pathology; Female; Fluorobenzenes - pharmacology; Fluorobenzenes - therapeutic use; Gene Expression Regulation - drug effects; Heptanoic Acids - pharmacology; Heptanoic Acids - therapeutic use; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Lipids - blood; Longevity - drug effects; Longevity - genetics; Male; MicroRNAs - genetics; MicroRNAs - metabolism; Oxidative Stress - drug effects; Pyrimidines - pharmacology; Pyrimidines - therapeutic use; Pyrroles - pharmacology; Pyrroles - therapeutic use; RNA, Messenger - genetics; RNA, Messenger - metabolism; Rosuvastatin Calcium; Sirtuin 1 - genetics; Sirtuin 1 - metabolism; Sulfonamides - pharmacology; Sulfonamides - therapeutic use; Transfection