Cyclization of 5,6-Diarylpyrrolo[3,4-d]pyrimidine-2,4-diones into Pyrrolo[1,2-f]phenanthridine Derivatives: Intramolecular C–H Arylation under Ru/NHC Catalysis

• Published in: Russian journal of general chemistry Vol. 94; no. 2; pp. 327 - 336
• Main Authors: Tkachenko, Yu. N., Shevchenko, M. A., Lavrentev, I. V., Pasyukov, D. V., Minyaev, M. E., Chernyshev, V. M.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.02.2024; Springer Nature; Springer Nature B.V
• Subjects: Catalysis; Catalytic activity; Chemistry; Chemistry and Materials Science; Chemistry, Multidisciplinary; Chemistry/Food Science; Diketones; Imidazole; Physical Sciences; Pyrimidines; Science & Technology; ruthenium; Ru/NHC; catalysis; intramolecular C–H arylation; pyrrolopyrimidine; pyrrolophenathridine; intramolecular C-H arylation; ACTIVATION; COMPLEXES; BOND FUNCTIONALIZATION

The cyclization of 5,6-diarylpyrrolo[3,4- d ]pyrimidine-2,4-diones containing a halogen atom in the ortho -position of one of the aryl rings, proceeding as intramolecular C–H arylation catalyzed by Ru(II) complexes, was studied. It was found that complexes Ru(NHC)(cymene)Cl 2 , where NHC = IPr [1,3-...