Distribution of polyglutamine proteins in Purkinje cells of the human and rat cerebellum

• Published in: Journal of evolutionary biochemistry and physiology Vol. 53; no. 4; pp. 340 - 342
• Main Authors: Gilerovich, E. G., Grigorev, I. P., Alekseeva, O. S., Kirik, O. V., Korzhevskii, D. E.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.07.2017; Springer Nature B.V
• Subjects: Animal Physiology; Biochemistry; Biomedical and Life Sciences; Cerebellum; Evolutionary Biology; Human subjects; Life Sciences; Polyglutamine; Purkinje cells; Rodents; Short Communications; Trinucleotide repeat diseases

In this work, localization of poly-glutamine proteins in the cerebellum is studied in human and rats, with the latter being a standard experimental organism for modeling brain pathologies