Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity - Vogel, Heike; Scherneck, Stephan; Kanzleiter, Timo; Benz, Verena; Kluge, Reinhart; Stadion, Mandy; Kryvych, Sergiy; Blüher, Matthias; Klöting, Nora; Joost, Hans-Georg; Schürmann, Annette (Human molecular genetics, 2012)
Keywords: 11-beta-Hydroxysteroid Dehydrogenase Type 1 - genetics; 11-beta-Hydroxysteroid Dehydrogenase Type 1 - metabolism; 5' Flanking Region - genetics; Adipose Tissue, White - metabolism; Adipose Tissue, White - pathology; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Biological and medical sciences; Body Weight - genetics; Chromosome Deletion; Chromosomes, Human, Pair 1 - genetics; Exons - genetics; Fundamental and applied biological sciences. Psychology; Gene Expression Profiling; Gene Expression Regulation; Genetics of eukaryotes. Biological and molecular evolution; Humans; Intracellular Signaling Peptides and Proteins - genetics; Medical sciences; Metabolic diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Middle Aged; Molecular and cellular biology; Multigene Family - genetics; Obesity; Obesity - enzymology; Obesity - genetics; Quantitative Trait Loci - genetics; Recombination, Genetic - genetics; RNA, Messenger - genetics; RNA, Messenger - metabolism; Young Adult; Chromosomal aberration; Obesity; Enzyme; Rodentia; Nutrition disorder; Chromosome 1; Vertebrata; Mammalia; Mouse; Animal; 11β-Hydroxysteroid dehydrogenase; Deletion; Development; Genetics; Oxidoreductases; Nutritional status