Transcriptional Profiling of Bone Regeneration

• Published in: The Journal of biological chemistry Vol. 277; no. 33; pp. 30177 - 30182
• Main Authors: Hadjiargyrou, Michael, Lombardo, Frank, Zhao, Shanchuan, Ahrens, William, Joo, Jungnam, Ahn, Hongshik, Jurman, Mark, White, David W., Rubin, Clinton T.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 16.08.2002; American Society for Biochemistry and Molecular Biology

The healing of skeletal fractures is essentially a replay of bone development, involving the closely regulated, interdependent processes of chondrogenesis and osteogenesis. Using a rat femur model of bone healing to determine the degree of transcriptional complexity of these processes, suppressive s...