Quantitative T2 MRI for bone marrow iron overload: normal reference values and assessment in thalassemia major patients

• Published in: Radiologia medica Vol. 127; no. 11; pp. 1199 - 1208
• Main Authors: Meloni, Antonella, Pistoia, Laura, Restaino, Gennaro, Missere, Massimiliano, Positano, Vincenzo, Spasiano, Anna, Casini, Tommaso, Cossu, Antonella, Cuccia, Liana, Massa, Antonella, Massei, Francesco, Cademartiri, Filippo
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.11.2022; Springer Nature B.V
• Subjects: Abdominal Radiology; Blood diseases; Bone marrow; Coefficient of variation; Correlation; Diagnostic Radiology; Females; Ferritin; Imaging; Interventional Radiology; Iron; Liver; Mathematical analysis; Medicine; Medicine & Public Health; Neuroradiology; Radiology; Reproducibility; Ultrasound; Vertebrae; Iron overload; Bone marrow; Lower limit of normal; Magnetic resonance imaging; Thalassemia major

Purpose We evaluated the feasibility and reproducibility of bone marrow T2* values and established the lower limit of normal in a cohort of healthy subjects. We investigated the clinical correlates of bone marrow T2* values in patients with thalassemia major (TM). Material and Methods Thirty healthy...