Successful Prolonged Desensitization to Epoetin-Alfa Hypersensitivity in an Adult Patient With Advanced Chronic Kidney Disease

• Published in: Curēus (Palo Alto, CA) Vol. 15; no. 6; p. e40424
• Main Authors: Panchal, Hemali, Ali, Saiyed, Hallett, Rosemary, Young, Brian, Wiegley, Nasim
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 14.06.2023; Cureus
• Subjects: Allergies; Allergy/Immunology; Anaphylaxis; Anemia; Blood transfusions; Case reports; Drug dosages; Immunology; Internal Medicine; Kidney diseases; Medicine; Nephrology; Patients; Sacramento California; United States > US; California; chronic kidney disease (ckd); anemia of chronic diseases; drug-induced hypersensitivity; synthetic epo; desensitization therapy

The use of erythropoiesis-stimulating agents (ESAs) reduces the need for recurrent blood transfusions in patients with advanced kidney disease. Rarely, allergic reactions to recombinant human erythropoietin can develop, complicating anemia management due to cross-reactivity between these agents. We...