Bringing amines back into aziridination

• Published in: Nature chemistry Vol. 13; no. 11; pp. 1027 - 1028
• Main Authors: Piou, Tiffany, Campeau, Louis-Charles
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.11.2021; Nature Publishing Group
• Subjects: 639/638/161; 639/638/549/933; Alkenes; Amines; Analytical Chemistry; Biochemistry; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Commodities; Electrochemistry; Inorganic Chemistry; Natural products; News & Views; news-and-views; Nitrogen; Organic Chemistry; Physical Chemistry; R&D; Research & development

Aziridines — three-membered nitrogen-containing heterocycles — are important synthetic targets, but N -alkyl aziridines are difficult to synthesize. Now, an electrochemical method, involving a dicationic intermediate, enables the coupling of alkenes and amines.