Bringing amines back into aziridination

Aziridines — three-membered nitrogen-containing heterocycles — are important synthetic targets, but N -alkyl aziridines are difficult to synthesize. Now, an electrochemical method, involving a dicationic intermediate, enables the coupling of alkenes and amines.

Saved in:
Bibliographic Details
Published inNature chemistry Vol. 13; no. 11; pp. 1027 - 1028
Main Authors Piou, Tiffany, Campeau, Louis-Charles
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.11.2021
Nature Publishing Group
Subjects
639/638/161
639/638/549/933
Alkenes
Amines
Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Commodities
Electrochemistry
Inorganic Chemistry
Natural products
News & Views
news-and-views
Nitrogen
Organic Chemistry
Physical Chemistry
R&D
Research & development
Online AccessGet full text

Cover

More Information
Summary:Aziridines — three-membered nitrogen-containing heterocycles — are important synthetic targets, but N -alkyl aziridines are difficult to synthesize. Now, an electrochemical method, involving a dicationic intermediate, enables the coupling of alkenes and amines.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:1755-4330
1755-4349
DOI:10.1038/s41557-021-00819-7