Muir-Torre Syndrome: Abdominal Sebaceous Carcinoma

A 56-year-old male with a past medical history of arachnoid cysts and with two previous brain operations and a ventriculoperitoneal shunt presented with a large left lower quadrant (LLQ) abdominal mass for one year, growing rapidly for the past three months. He endorsed pus and blood leaking from ul...

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Published inCurēus (Palo Alto, CA) Vol. 14; no. 12; p. e33103
Main Authors Bui, An, Shah, Shalini, Winston, Nutan, Mahmoud, Ahmed
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 29.12.2022
Cureus
Subjects
Abdomen
Blood
Brain diseases
Colorectal cancer
Cysts
Family medical history
General Surgery
Genes
Mutation
Ovaries
Pathology
Patients
Plastic Surgery
Proteins
Tumors
Urogenital system
United States > US
muir torre syndrome
abdominal cystic mass
muir-torre syndrome
sebaceous gland
sebaceous carcinoma
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Summary:A 56-year-old male with a past medical history of arachnoid cysts and with two previous brain operations and a ventriculoperitoneal shunt presented with a large left lower quadrant (LLQ) abdominal mass for one year, growing rapidly for the past three months. He endorsed pus and blood leaking from ulceration on the lateral underside of the mass, and a section of the mass ruptured with blood and pus draining out on the day of admission. He denied any fevers, chills, pain, or numbness in the mass or any history of similar masses. Of note, the patient has an extensive familial history of cancer including colorectal cancer in his mother in her 30s. Computed tomography and biopsy of mass were concerning for malignancy, reporting a neoplasm in the dermis that grows in round and irregular lobules of cells along with the majority of the cells having oval nuclei with areas of sebaceous differentiation. Pathology showed sebaceous carcinoma with concern for Muir-Torre syndrome. The patient was discharged and instructed to follow up with oncology and gastroenterology.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.33103