Spindle Cell Squamous Cell Carcinoma of the Scalp Treated With Pembrolizumab Cisplatin and 5-Fluorouracil

• Published in: Curēus (Palo Alto, CA) Vol. 13; no. 12; p. e20242
• Main Authors: Alzahrani, Ali M, Al Mutari, Bander, Alzahrani, Anas, Alkhodaidi, Abdelhafeeth, Yahya, Gaaem
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 07.12.2021; Cureus
• Subjects: Cancer; Case reports; Chemotherapy; Cytokeratin; FDA approval; Hospitals; Immunotherapy; Lymphatic system; Magnetic resonance imaging; Medical imaging; Metastasis; Monoclonal antibodies; Oncology; Pathology; Patients; Proteins; Radiation therapy; Squamous cell carcinoma; Surgery; Targeted cancer therapy; pembrolizumab; scalp; cutaneous carcinosarcoma; immunotherapy; spindle cell carcinoma

Cutaneous spindle cell squamous cell carcinoma (SpSCC) of the head and neck is a very rare tumor. It is an aggressive variant of squamous cell carcinoma. The usual treatment of the localized disease is surgery with or without radiotherapy. No standard treatment for metastatic disease although some c...