The LEVANT I (Lutonix Paclitaxel-Coated Balloon for the Prevention of Femoropopliteal Restenosis) Trial for Femoropopliteal Revascularization

• Published in: JACC. Cardiovascular interventions Vol. 7; no. 1; pp. 10 - 19
• Main Authors: Scheinert, Dierk, MD, Duda, Stephan, MD, Zeller, Thomas, MD, Krankenberg, Hans, MD, Ricke, Jens, MD, Bosiers, Marc, MD, Tepe, Gunnar, MD, Naisbitt, Scott, MD, PhD, Rosenfield, Kenneth, MD
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 2014
• Subjects: angioplasty; Cardiovascular; drug-coated balloon; drug-eluting balloon; paclitaxel; peripheral vascular disease; restenosis; paclitaxel; restenosis; DCB; drug-coated balloon(s); drug-eluting balloon; ITT; drug-coated balloon; LLL; peripheral vascular disease; intention to treat; target lesion revascularization(s); late lumen loss; pharmacokinetics; PK; TLR; angioplasty

Objectives This study sought to evaluate the safety and efficacy of the Lutonix drug-coated balloon (DCB) coated with 2 μg/mm2 paclitaxel and a polysorbate/sorbitol carrier for treatment of femoropopliteal lesions. Background Percutaneous treatment of peripheral vascular disease is associated with a...