Safety and Efficacy of New-Generation Drug-Eluting Stents in Women Undergoing Complex Percutaneous Coronary Artery Revascularization
Abstract Objectives The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI). Background Whether the benefits of new-generation DES are preserved...
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Published in | JACC. Cardiovascular interventions Vol. 9; no. 7; pp. 674 - 684 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier Inc
01.04.2016
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Abstract | Abstract Objectives The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI). Background Whether the benefits of new-generation DES are preserved in women undergoing complex percutaneous revascularization is unknown. Methods We pooled patient-level data from women enrolled in 26 randomized trials of DES. Study population was categorized according to the presence or absence of CPCI, which was defined as the composite of total stent length >30 mm, ≥2 stents implanted, ≥2 lesions treated, or bifurcation lesion as target vessel. The primary endpoint was major adverse cardiovascular events (MACE) defined as a composite of all-cause mortality, myocardial infarction, or target lesion revascularization at 3 years of follow-up. Results Of 10,241 women included in the pooled database, 4,629 (45%) underwent CPCI. Compared with non-CPCI, women who underwent CPCI had a higher 3-year risk of MACE (adjusted hazard ratio [HR]: 1.63; 95% confidence interval [CI]: 1.45 to 1.83; p < 0.0001). In women who underwent CPCI, use of new-generation DES was associated with significantly lower 3-year risk of MACE (adjusted HR: 0.81; 95% CI: 0.68 to 0.96), target lesion revascularization (adjusted HR: 0.74; 95% CI: 0.57 to 0.95), and definite or probable stent thrombosis (ST) (adjusted HR: 0.50; 95% CI: 0.30 to 0.83). The benefit of new-generation DES on efficacy and safety outcomes was uniform between CPCI and non-CPCI groups, without evidence of interaction. By landmark analysis, new-generation DES were associated with low rates (≤0.4%) of very-late ST irrespective of procedural complexity. Conclusions Women undergoing CPCI remain at higher risk of adverse events. The long-term ischemic benefits of new-generation DES platforms are uniform among complex and non-complex percutaneous revascularization procedures in women. |
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AbstractList | The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI).
Whether the benefits of new-generation DES are preserved in women undergoing complex percutaneous revascularization is unknown.
We pooled patient-level data from women enrolled in 26 randomized trials of DES. Study population was categorized according to the presence or absence of CPCI, which was defined as the composite of total stent length >30 mm, ≥2 stents implanted, ≥2 lesions treated, or bifurcation lesion as target vessel. The primary endpoint was major adverse cardiovascular events (MACE) defined as a composite of all-cause mortality, myocardial infarction, or target lesion revascularization at 3 years of follow-up.
Of 10,241 women included in the pooled database, 4,629 (45%) underwent CPCI. Compared with non-CPCI, women who underwent CPCI had a higher 3-year risk of MACE (adjusted hazard ratio [HR]: 1.63; 95% confidence interval [CI]: 1.45 to 1.83; p < 0.0001). In women who underwent CPCI, use of new-generation DES was associated with significantly lower 3-year risk of MACE (adjusted HR: 0.81; 95% CI: 0.68 to 0.96), target lesion revascularization (adjusted HR: 0.74; 95% CI: 0.57 to 0.95), and definite or probable stent thrombosis (ST) (adjusted HR: 0.50; 95% CI: 0.30 to 0.83). The benefit of new-generation DES on efficacy and safety outcomes was uniform between CPCI and non-CPCI groups, without evidence of interaction. By landmark analysis, new-generation DES were associated with low rates (≤0.4%) of very-late ST irrespective of procedural complexity.
Women undergoing CPCI remain at higher risk of adverse events. The long-term ischemic benefits of new-generation DES platforms are uniform among complex and non-complex percutaneous revascularization procedures in women. Abstract Objectives The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI). Background Whether the benefits of new-generation DES are preserved in women undergoing complex percutaneous revascularization is unknown. Methods We pooled patient-level data from women enrolled in 26 randomized trials of DES. Study population was categorized according to the presence or absence of CPCI, which was defined as the composite of total stent length >30 mm, ≥2 stents implanted, ≥2 lesions treated, or bifurcation lesion as target vessel. The primary endpoint was major adverse cardiovascular events (MACE) defined as a composite of all-cause mortality, myocardial infarction, or target lesion revascularization at 3 years of follow-up. Results Of 10,241 women included in the pooled database, 4,629 (45%) underwent CPCI. Compared with non-CPCI, women who underwent CPCI had a higher 3-year risk of MACE (adjusted hazard ratio [HR]: 1.63; 95% confidence interval [CI]: 1.45 to 1.83; p < 0.0001). In women who underwent CPCI, use of new-generation DES was associated with significantly lower 3-year risk of MACE (adjusted HR: 0.81; 95% CI: 0.68 to 0.96), target lesion revascularization (adjusted HR: 0.74; 95% CI: 0.57 to 0.95), and definite or probable stent thrombosis (ST) (adjusted HR: 0.50; 95% CI: 0.30 to 0.83). The benefit of new-generation DES on efficacy and safety outcomes was uniform between CPCI and non-CPCI groups, without evidence of interaction. By landmark analysis, new-generation DES were associated with low rates (≤0.4%) of very-late ST irrespective of procedural complexity. Conclusions Women undergoing CPCI remain at higher risk of adverse events. The long-term ischemic benefits of new-generation DES platforms are uniform among complex and non-complex percutaneous revascularization procedures in women. |
Author | Mikhail, Ghada W., MD Von Birgelen, Clemens, MD Kimura, Takeshi, MD Mehran, Roxana, MD Salianski, Olga Chandrasekhar, Jaya, MBBS Stone, Gregg W., MD Kastrati, Adnan, MD Genereux, Philippe, MD Giustino, Gennaro, MD Sartori, Samantha, PhD Stefanini, Giulio G., MD, PhD Serruys, Patrick W., MD, PhD Jeger, Raban V., MD Mehta, Laxmi, MD Steg, P. Gabriel, MD, PhD Camenzind, Edoardo, MD Wijns, William, MD Saporito, Robert Kim, Hyo-Soo, MD Leon, Martin B., MD Valgimigli, Marco, MD, PhD Itchhaporia, Dipti, MD Smits, Pieter C., MD Dangas, George D., MD, PhD Ortega, Rebecca, MHA Weisz, Giora, MD Windecker, Stephan, MD, PhD Galatius, Soren, MD Baber, Usman, MD, MSc Morice, Marie-Claude, MD Kandzari, David E., MD Aquino, Melissa, MSc Chieffo, Alaide, MD |
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Cites_doi | 10.1016/S0140-6736(12)60324-9 10.1016/j.jacc.2010.07.028 10.1001/jama.297.18.2001 10.1016/j.jacc.2015.01.039 10.1016/j.jacc.2011.06.049 10.4244/EIJV8I1A13 10.1016/j.jacc.2014.01.034 10.1161/CIRCULATIONAHA.105.601823 10.1016/S0140-6736(13)60141-5 10.1016/j.amjcard.2013.05.003 10.1016/j.amjcard.2009.01.031 10.1038/nrcardio.2010.116 10.1016/S0140-6736(13)61782-1 10.1056/NEJMoa1412168 10.1016/j.jacc.2011.07.031 10.1016/j.jacc.2012.03.010 10.1161/CIRCULATIONAHA.112.104059 10.1056/NEJMoa1415447 10.1016/j.amjcard.2015.06.010 10.1161/CIRCULATIONAHA.108.826479 10.1016/j.jcin.2008.08.021 10.1016/j.jacc.2008.07.006 10.1056/NEJMoa067193 10.1016/j.amjcard.2005.11.081 10.1016/S0140-6736(15)60263-X 10.1161/CIRCULATIONAHA.112.097014 10.4244/EIJV8I11A197 10.1016/j.hlc.2008.08.002 10.1016/j.jacc.2009.10.014 10.1016/j.jacc.2011.01.036 |
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Keywords | coronary artery disease ST RCT target lesion revascularization CAD myocardial infarction CPCI drug-eluting stent(s) randomized controlled trial percutaneous coronary intervention complex PCI DES outcomes stent thrombosis complex percutaneous coronary intervention PCI TLR MI women |
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References | Qian, Maehara, Mintz (bib6) 2009; 103 Palmerini, Biondi-Zoccai, Della Riva (bib24) 2012; 379 Stone, Moses, Ellis (bib18) 2007; 356 Dangas, Claessen, Caixeta, Sanidas, Mintz, Mehran (bib11) 2010; 56 Kapur, Hall, Malik (bib13) 2010; 55 Kirtane, Gupta, Iyengar (bib17) 2009; 119 Palmerini, Benedetto, Bacchi-Reggiani (bib25) 2015; 385 Giustino, Baber, Sartori (bib26) 2015; 65 Oqueli, Baker, Carroll, Hiscock, Dick (bib9) 2008; 17 Win, Caldera, Maresh (bib16) 2007; 297 Mohr, Morice, Kappetein (bib19) 2013; 381 Park, Chae, Lim (bib29) 2011; 58 Hendry, Fraser, Eichhofer (bib10) 2012; 8 Genereux, Palmerini, Caixeta (bib23) 2012; 59 Kastrati, Dibra, Mehilli (bib12) 2006; 113 Hannan, Wu, Walford (bib21) 2009; 2 Park, Ahn, Kim (bib30) 2015; 372 Bangalore, Guo, Samadashvili (bib31) 2015; 372 Baber, Kini, Sharma (bib5) 2010; 7 Malkin, George, Ghobrial (bib22) 2013; 8 Rao, Shaw, Brindis, Klein, Weintraub, Peterson (bib3) 2006; 97 Stefanini, Serruys, Silber (bib4) 2011; 57 Baber, Mehran, Sharma (bib28) 2011; 58 Srinivas, Garg, Negassa, Bang, Monrad (bib7) 2007; 19 Wu, Dyer, Walford (bib20) 2013; 112 Wenaweser, Daemen, Zwahlen (bib2) 2008; 52 Giustino, Baber, Stefanini (bib14) 2015; 116 Bangalore, Kumar, Fusaro (bib1) 2012; 125 Généreux, Madhavan, Mintz (bib8) 2014; 63 Stefanini, Baber, Windecker (bib15) 2013; 382 Kimura, Morimoto, Natsuaki (bib27) 2012; 126 Baber (10.1016/j.jcin.2015.12.013_bib28) 2011; 58 Palmerini (10.1016/j.jcin.2015.12.013_bib25) 2015; 385 Stefanini (10.1016/j.jcin.2015.12.013_bib4) 2011; 57 Baber (10.1016/j.jcin.2015.12.013_bib5) 2010; 7 Bangalore (10.1016/j.jcin.2015.12.013_bib31) 2015; 372 Giustino (10.1016/j.jcin.2015.12.013_bib26) 2015; 65 Stefanini (10.1016/j.jcin.2015.12.013_bib15) 2013; 382 Hannan (10.1016/j.jcin.2015.12.013_bib21) 2009; 2 Palmerini (10.1016/j.jcin.2015.12.013_bib24) 2012; 379 Park (10.1016/j.jcin.2015.12.013_bib30) 2015; 372 Kimura (10.1016/j.jcin.2015.12.013_bib27) 2012; 126 Giustino (10.1016/j.jcin.2015.12.013_bib14) 2015; 116 Kirtane (10.1016/j.jcin.2015.12.013_bib17) 2009; 119 Dangas (10.1016/j.jcin.2015.12.013_bib11) 2010; 56 Malkin (10.1016/j.jcin.2015.12.013_bib22) 2013; 8 Kapur (10.1016/j.jcin.2015.12.013_bib13) 2010; 55 Win (10.1016/j.jcin.2015.12.013_bib16) 2007; 297 Genereux (10.1016/j.jcin.2015.12.013_bib23) 2012; 59 Qian (10.1016/j.jcin.2015.12.013_bib6) 2009; 103 Bangalore (10.1016/j.jcin.2015.12.013_bib1) 2012; 125 Park (10.1016/j.jcin.2015.12.013_bib29) 2011; 58 Rao (10.1016/j.jcin.2015.12.013_bib3) 2006; 97 Wenaweser (10.1016/j.jcin.2015.12.013_bib2) 2008; 52 Mohr (10.1016/j.jcin.2015.12.013_bib19) 2013; 381 Stone (10.1016/j.jcin.2015.12.013_bib18) 2007; 356 Généreux (10.1016/j.jcin.2015.12.013_bib8) 2014; 63 Hendry (10.1016/j.jcin.2015.12.013_bib10) 2012; 8 Wu (10.1016/j.jcin.2015.12.013_bib20) 2013; 112 Srinivas (10.1016/j.jcin.2015.12.013_bib7) 2007; 19 Oqueli (10.1016/j.jcin.2015.12.013_bib9) 2008; 17 Kastrati (10.1016/j.jcin.2015.12.013_bib12) 2006; 113 |
References_xml | – volume: 8 start-page: 79 year: 2012 end-page: 86 ident: bib10 article-title: Coronary perforation in the drug-eluting stent era: incidence, risk factors, management and outcome: the UK experience publication-title: EuroIntervention contributor: fullname: Eichhofer – volume: 126 start-page: 1225 year: 2012 end-page: 1236 ident: bib27 article-title: Comparison of everolimus-eluting and sirolimus-eluting coronary stents: 1-year outcomes from the Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting stent Trial (RESET) publication-title: Circulation contributor: fullname: Natsuaki – volume: 17 start-page: S55 year: 2008 end-page: S62 ident: bib9 article-title: Percutaneous coronary intervention in women: in-hospital clinical outcome: experience from a single private institution in Melbourne publication-title: Heart Lung Circ contributor: fullname: Dick – volume: 372 start-page: 1204 year: 2015 end-page: 1212 ident: bib30 article-title: Trial of everolimus-eluting stents or bypass surgery for coronary disease publication-title: N Engl J Med contributor: fullname: Kim – volume: 297 start-page: 2001 year: 2007 end-page: 2009 ident: bib16 article-title: Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents publication-title: JAMA contributor: fullname: Maresh – volume: 65 start-page: 1298 year: 2015 end-page: 1310 ident: bib26 article-title: Duration of dual antiplatelet therapy after drug-eluting stent implantation: a systematic review and meta-analysis of randomized controlled trials publication-title: J Am Coll Cardiol contributor: fullname: Sartori – volume: 52 start-page: 1134 year: 2008 end-page: 1140 ident: bib2 article-title: Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice: 4-year results from a large 2-institutional cohort study publication-title: J Am Coll Cardiol contributor: fullname: Zwahlen – volume: 97 start-page: 1478 year: 2006 end-page: 1481 ident: bib3 article-title: On- versus off-label use of drug-eluting coronary stents in clinical practice (report from the American College of Cardiology National Cardiovascular Data Registry [NCDR]) publication-title: Am J Cardiol contributor: fullname: Peterson – volume: 119 start-page: 3198 year: 2009 end-page: 3206 ident: bib17 article-title: Safety and efficacy of drug-eluting and bare metal stents: comprehensive meta-analysis of randomized trials and observational studies publication-title: Circulation contributor: fullname: Iyengar – volume: 2 start-page: 17 year: 2009 end-page: 25 ident: bib21 article-title: Incomplete revascularization in the era of drug-eluting stents: impact on adverse outcomes publication-title: J Am Coll Cardiol Intv contributor: fullname: Walford – volume: 7 start-page: 485 year: 2010 end-page: 496 ident: bib5 article-title: Stenting of complex lesions: an overview publication-title: Nat Rev Cardiol contributor: fullname: Sharma – volume: 382 start-page: 1879 year: 2013 end-page: 1888 ident: bib15 article-title: Safety and efficacy of drug-eluting stents in women: a patient-level pooled analysis of randomised trials publication-title: Lancet contributor: fullname: Windecker – volume: 56 start-page: 1897 year: 2010 end-page: 1907 ident: bib11 article-title: In-stent restenosis in the drug-eluting stent era publication-title: J Am Coll Cardiol contributor: fullname: Mehran – volume: 116 start-page: 845 year: 2015 end-page: 852 ident: bib14 article-title: Impact of clinical presentation (stable angina pectoris vs unstable angina pectoris or non-ST-elevation myocardial infarction vs ST-elevation myocardial infarction) on long-term outcomes in women undergoing percutaneous coronary intervention with drug-eluting stents publication-title: Am J Cardiol contributor: fullname: Stefanini – volume: 63 start-page: 1845 year: 2014 end-page: 1854 ident: bib8 article-title: Ischemic outcomes after coronary intervention of calcified vessels in acute coronary syndromes: pooled analysis from the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trials publication-title: J Am Coll Cardiol contributor: fullname: Mintz – volume: 8 start-page: 1286 year: 2013 end-page: 1295 ident: bib22 article-title: Residual SYNTAX score after PCI for triple vessel coronary artery disease: quantifying the adverse effect of incomplete revascularisation publication-title: EuroIntervention contributor: fullname: Ghobrial – volume: 103 start-page: 1210 year: 2009 end-page: 1214 ident: bib6 article-title: Impact of gender and age on in vivo virtual histology–intravascular ultrasound imaging plaque characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry) publication-title: Am J Cardiol contributor: fullname: Mintz – volume: 19 start-page: 265 year: 2007 end-page: 268 ident: bib7 article-title: Persistent sex difference in hospital outcome following percutaneous coronary intervention: results from the New York State reporting system publication-title: J Invasive Cardiol contributor: fullname: Monrad – volume: 58 start-page: 1844 year: 2011 end-page: 1854 ident: bib29 article-title: Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial publication-title: J Am Coll Cardiol contributor: fullname: Lim – volume: 58 start-page: 1569 year: 2011 end-page: 1577 ident: bib28 article-title: Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials publication-title: J Am Coll Cardiol contributor: fullname: Sharma – volume: 55 start-page: 432 year: 2010 end-page: 440 ident: bib13 article-title: Randomized comparison of percutaneous coronary intervention with coronary artery bypass grafting in diabetic patients: 1-year results of the CARDia (Coronary Artery Revascularization in Diabetes) trial publication-title: J Am Coll Cardiol contributor: fullname: Malik – volume: 59 start-page: 2165 year: 2012 end-page: 2174 ident: bib23 article-title: Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score publication-title: J Am Coll Cardiol contributor: fullname: Caixeta – volume: 372 start-page: 1213 year: 2015 end-page: 1222 ident: bib31 article-title: Everolimus-eluting stents or bypass surgery for multivessel coronary disease publication-title: The New England journal of medicine contributor: fullname: Samadashvili – volume: 57 start-page: 2221 year: 2011 end-page: 2232 ident: bib4 article-title: The impact of patient and lesion complexity on clinical and angiographic outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial (a randomized comparison of a zotarolimus-eluting stent with an everolimus-eluting stent for percutaneous coronary intervention) publication-title: J Am Coll Cardiol contributor: fullname: Silber – volume: 385 start-page: 2371 year: 2015 end-page: 2382 ident: bib25 article-title: Mortality in patients treated with extended duration dual antiplatelet therapy after drug-eluting stent implantation: a pairwise and Bayesian network meta-analysis of randomised trials publication-title: Lancet contributor: fullname: Bacchi-Reggiani – volume: 381 start-page: 629 year: 2013 end-page: 638 ident: bib19 article-title: Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial publication-title: Lancet contributor: fullname: Kappetein – volume: 112 start-page: 775 year: 2013 end-page: 781 ident: bib20 article-title: Incomplete revascularization is associated with greater risk of long-term mortality after stenting in the era of first generation drug-eluting stents publication-title: Am J Cardiol contributor: fullname: Walford – volume: 379 start-page: 1393 year: 2012 end-page: 1402 ident: bib24 article-title: Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis publication-title: Lancet contributor: fullname: Della Riva – volume: 113 start-page: 2293 year: 2006 end-page: 2300 ident: bib12 article-title: Predictive factors of restenosis after coronary implantation of sirolimus- or paclitaxel-eluting stents publication-title: Circulation contributor: fullname: Mehilli – volume: 356 start-page: 998 year: 2007 end-page: 1008 ident: bib18 article-title: Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents publication-title: N Engl J Med contributor: fullname: Ellis – volume: 125 start-page: 2873 year: 2012 end-page: 2891 ident: bib1 article-title: Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials publication-title: Circulation contributor: fullname: Fusaro – volume: 379 start-page: 1393 year: 2012 ident: 10.1016/j.jcin.2015.12.013_bib24 article-title: Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis publication-title: Lancet doi: 10.1016/S0140-6736(12)60324-9 contributor: fullname: Palmerini – volume: 56 start-page: 1897 year: 2010 ident: 10.1016/j.jcin.2015.12.013_bib11 article-title: In-stent restenosis in the drug-eluting stent era publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2010.07.028 contributor: fullname: Dangas – volume: 297 start-page: 2001 year: 2007 ident: 10.1016/j.jcin.2015.12.013_bib16 article-title: Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents publication-title: JAMA doi: 10.1001/jama.297.18.2001 contributor: fullname: Win – volume: 65 start-page: 1298 year: 2015 ident: 10.1016/j.jcin.2015.12.013_bib26 article-title: Duration of dual antiplatelet therapy after drug-eluting stent implantation: a systematic review and meta-analysis of randomized controlled trials publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2015.01.039 contributor: fullname: Giustino – volume: 58 start-page: 1569 year: 2011 ident: 10.1016/j.jcin.2015.12.013_bib28 article-title: Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.06.049 contributor: fullname: Baber – volume: 19 start-page: 265 year: 2007 ident: 10.1016/j.jcin.2015.12.013_bib7 article-title: Persistent sex difference in hospital outcome following percutaneous coronary intervention: results from the New York State reporting system publication-title: J Invasive Cardiol contributor: fullname: Srinivas – volume: 8 start-page: 79 year: 2012 ident: 10.1016/j.jcin.2015.12.013_bib10 article-title: Coronary perforation in the drug-eluting stent era: incidence, risk factors, management and outcome: the UK experience publication-title: EuroIntervention doi: 10.4244/EIJV8I1A13 contributor: fullname: Hendry – volume: 63 start-page: 1845 year: 2014 ident: 10.1016/j.jcin.2015.12.013_bib8 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2014.01.034 contributor: fullname: Généreux – volume: 113 start-page: 2293 year: 2006 ident: 10.1016/j.jcin.2015.12.013_bib12 article-title: Predictive factors of restenosis after coronary implantation of sirolimus- or paclitaxel-eluting stents publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.105.601823 contributor: fullname: Kastrati – volume: 381 start-page: 629 year: 2013 ident: 10.1016/j.jcin.2015.12.013_bib19 article-title: Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial publication-title: Lancet doi: 10.1016/S0140-6736(13)60141-5 contributor: fullname: Mohr – volume: 112 start-page: 775 year: 2013 ident: 10.1016/j.jcin.2015.12.013_bib20 article-title: Incomplete revascularization is associated with greater risk of long-term mortality after stenting in the era of first generation drug-eluting stents publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2013.05.003 contributor: fullname: Wu – volume: 103 start-page: 1210 year: 2009 ident: 10.1016/j.jcin.2015.12.013_bib6 article-title: Impact of gender and age on in vivo virtual histology–intravascular ultrasound imaging plaque characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry) publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2009.01.031 contributor: fullname: Qian – volume: 7 start-page: 485 year: 2010 ident: 10.1016/j.jcin.2015.12.013_bib5 article-title: Stenting of complex lesions: an overview publication-title: Nat Rev Cardiol doi: 10.1038/nrcardio.2010.116 contributor: fullname: Baber – volume: 382 start-page: 1879 year: 2013 ident: 10.1016/j.jcin.2015.12.013_bib15 article-title: Safety and efficacy of drug-eluting stents in women: a patient-level pooled analysis of randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(13)61782-1 contributor: fullname: Stefanini – volume: 372 start-page: 1213 year: 2015 ident: 10.1016/j.jcin.2015.12.013_bib31 article-title: Everolimus-eluting stents or bypass surgery for multivessel coronary disease publication-title: The New England journal of medicine doi: 10.1056/NEJMoa1412168 contributor: fullname: Bangalore – volume: 58 start-page: 1844 year: 2011 ident: 10.1016/j.jcin.2015.12.013_bib29 article-title: Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.07.031 contributor: fullname: Park – volume: 59 start-page: 2165 year: 2012 ident: 10.1016/j.jcin.2015.12.013_bib23 article-title: Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2012.03.010 contributor: fullname: Genereux – volume: 126 start-page: 1225 year: 2012 ident: 10.1016/j.jcin.2015.12.013_bib27 article-title: Comparison of everolimus-eluting and sirolimus-eluting coronary stents: 1-year outcomes from the Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting stent Trial (RESET) publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.112.104059 contributor: fullname: Kimura – volume: 372 start-page: 1204 year: 2015 ident: 10.1016/j.jcin.2015.12.013_bib30 article-title: Trial of everolimus-eluting stents or bypass surgery for coronary disease publication-title: N Engl J Med doi: 10.1056/NEJMoa1415447 contributor: fullname: Park – volume: 116 start-page: 845 year: 2015 ident: 10.1016/j.jcin.2015.12.013_bib14 publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2015.06.010 contributor: fullname: Giustino – volume: 119 start-page: 3198 year: 2009 ident: 10.1016/j.jcin.2015.12.013_bib17 article-title: Safety and efficacy of drug-eluting and bare metal stents: comprehensive meta-analysis of randomized trials and observational studies publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.826479 contributor: fullname: Kirtane – volume: 2 start-page: 17 year: 2009 ident: 10.1016/j.jcin.2015.12.013_bib21 article-title: Incomplete revascularization in the era of drug-eluting stents: impact on adverse outcomes publication-title: J Am Coll Cardiol Intv doi: 10.1016/j.jcin.2008.08.021 contributor: fullname: Hannan – volume: 52 start-page: 1134 year: 2008 ident: 10.1016/j.jcin.2015.12.013_bib2 article-title: Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice: 4-year results from a large 2-institutional cohort study publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2008.07.006 contributor: fullname: Wenaweser – volume: 356 start-page: 998 year: 2007 ident: 10.1016/j.jcin.2015.12.013_bib18 article-title: Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents publication-title: N Engl J Med doi: 10.1056/NEJMoa067193 contributor: fullname: Stone – volume: 97 start-page: 1478 year: 2006 ident: 10.1016/j.jcin.2015.12.013_bib3 article-title: On- versus off-label use of drug-eluting coronary stents in clinical practice (report from the American College of Cardiology National Cardiovascular Data Registry [NCDR]) publication-title: Am J Cardiol doi: 10.1016/j.amjcard.2005.11.081 contributor: fullname: Rao – volume: 385 start-page: 2371 year: 2015 ident: 10.1016/j.jcin.2015.12.013_bib25 article-title: Mortality in patients treated with extended duration dual antiplatelet therapy after drug-eluting stent implantation: a pairwise and Bayesian network meta-analysis of randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(15)60263-X contributor: fullname: Palmerini – volume: 125 start-page: 2873 year: 2012 ident: 10.1016/j.jcin.2015.12.013_bib1 article-title: Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.112.097014 contributor: fullname: Bangalore – volume: 8 start-page: 1286 year: 2013 ident: 10.1016/j.jcin.2015.12.013_bib22 article-title: Residual SYNTAX score after PCI for triple vessel coronary artery disease: quantifying the adverse effect of incomplete revascularisation publication-title: EuroIntervention doi: 10.4244/EIJV8I11A197 contributor: fullname: Malkin – volume: 17 start-page: S55 issue: Suppl 4 year: 2008 ident: 10.1016/j.jcin.2015.12.013_bib9 article-title: Percutaneous coronary intervention in women: in-hospital clinical outcome: experience from a single private institution in Melbourne publication-title: Heart Lung Circ doi: 10.1016/j.hlc.2008.08.002 contributor: fullname: Oqueli – volume: 55 start-page: 432 year: 2010 ident: 10.1016/j.jcin.2015.12.013_bib13 article-title: Randomized comparison of percutaneous coronary intervention with coronary artery bypass grafting in diabetic patients: 1-year results of the CARDia (Coronary Artery Revascularization in Diabetes) trial publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2009.10.014 contributor: fullname: Kapur – volume: 57 start-page: 2221 year: 2011 ident: 10.1016/j.jcin.2015.12.013_bib4 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2011.01.036 contributor: fullname: Stefanini |
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Snippet | Abstract Objectives The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation... The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women... |
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SubjectTerms | Cardiovascular complex PCI drug-eluting stent(s) outcomes women |
Title | Safety and Efficacy of New-Generation Drug-Eluting Stents in Women Undergoing Complex Percutaneous Coronary Artery Revascularization |
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