The use of nanoparticles in wound treatment: a systematic review

• Published in: Revista da Escola de Enfermagem da U S P Vol. 51; p. e03272
• Main Authors: Silva, Maria Michelle Pereira, Aguiar, Maria Isis Freire de, Rodrigues, Andrea Bezerra, Miranda, Maira Di Ciero, Araújo, Michell Ângelo Marques, Rolim, Isaura Letícia Tavares Palmeira, Souza, Angela Maria Alves E
• Format: Journal Article
• Language: Portuguese
• Published: Brazil 08.01.2018
• Subjects: Animals; Anti-Bacterial Agents - administration & dosage; Burns - drug therapy; Humans; Nanoparticles; Surgical Wound Infection - drug therapy; Wound Healing - drug effects; Wounds and Injuries - drug therapy
• ISSN: 0080-6234; 1980-220X
• DOI: 10.1590/S1980-220X2016043503272

To analyze the effects of nanoparticle-based dressings on the wound healing process in in vitro animals and human cells based on scientific evidence. A systematic review of the literature in LILACS, PubMed and Science Direct databases. The articles were selected and evaluated for the level of evidence by the application of STROBE. The sample consisted of 12 articles. The application of the products occurred in surgical wounds, burns, infected wounds and gingival ulcers in laboratory animals, as well as in vitro tests, demonstrating that among other advantages, the nanoparticle-based dressings increased the healing speed, had good antibacterial capacity and were non cytotoxic agents. Based on the analyzed articles, it can be affirmed that dressings containing nanocomposites are quite promising and are shown as a great therapeutic option in wound healing.