Reliable calibration and validation of phenomenological and hybrid models of high-cell-density fed-batch cultures subject to metabolic overflow - Ibáñez, Francisco; Puentes-Cantor, Hernán; Bárzaga-Martell, Lisbel; Saa, Pedro A.; Agosin, Eduardo; Pérez-Correa, José Ricardo (Computers & chemical engineering, 2024)
Keywords: Dynamic optimization; Fed-batch fermentation; High-density cultures; Hybrid models; Overflow metabolism; Physics-informed neural networks; Overflow metabolism; High-density cultures; Hybrid models; Physics-informed neural networks; Dynamic optimization; Fed-batch fermentation