Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings

• Published in: Addiction biology Vol. 30; no. 8; pp. e70067 - n/a
• Main Authors: Kleinhans, Natalia M., Terry, Garth E., Kang, Dahyeon, Larsen, Sarah F., Larimer, Mary E.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.08.2025
• Subjects: Addictions; Adult; anticorrelation; Cannabis; Corpus Striatum - diagnostic imaging; Corpus Striatum - physiopathology; craving; Craving - physiology; Cues; Drug abuse; Female; Functional magnetic resonance imaging; Humans; Magnetic Resonance Imaging; Male; Marijuana; Marijuana Abuse - diagnostic imaging; Marijuana Abuse - physiopathology; Neostriatum; Neural Pathways - diagnostic imaging; Neural Pathways - physiopathology; nucleus accumbens; resting‐state fMRI; Substance use; ventral tegmental area; Ventral Tegmental Area - diagnostic imaging; Ventral Tegmental Area - physiopathology; Ventral tegmentum; Visual stimuli; VTA; Young Adult; craving; VTA; anticorrelation; ventral tegmental area; marijuana; nucleus accumbens; resting‐state fMRI

ABSTRACT Cue‐induced craving—the desire to use a drug triggered by exposure to cues associated with prior use—is a central mechanism in the development and maintenance of problematic substance use behaviours. Drug cues have the power to induce craving even in long‐term abstinent individuals, which h...