Changes of glucocorticoid level in plasma and adrenal glands of pregnant rats and their offspring after antenatal stress of different etiology

We investigated the glucocorticoid level in plasma and adrenal glands of pregnant rats in the period of early organogenesis. Tests were performed 24 hours after stress of different etiology (acute hypobaric hypoxia, intermittent normobaric hypoxia, and immobilization) and then repeated in the adult...

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Published inBiology bulletin of the Russian Academy of Sciences Vol. 38; no. 1; pp. 87 - 91
Main Authors Trofimova, L. K, Baizhumanov, A. A, Goncharenko, E. N, Krushinskaya, Ya. V, Sokolova, N. A, Kudryashova, N. Yu
Format Journal Article
LanguageEnglish
Published Dordrecht Dordrecht : SP MAIK Nauka/Interperiodica 01.02.2011
SP MAIK Nauka/Interperiodica
Subjects
Biochemistry
Biomedical and Life Sciences
Cell Biology
Ecology
Life Sciences
Short Communication
Zoology
Female Offspring
Prenatal Stress
Glucocorticoid Level
Adrenal Gland
Biology Bulletin
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Summary:We investigated the glucocorticoid level in plasma and adrenal glands of pregnant rats in the period of early organogenesis. Tests were performed 24 hours after stress of different etiology (acute hypobaric hypoxia, intermittent normobaric hypoxia, and immobilization) and then repeated in the adult offspring. There was a significant decrease in the glucocorticoid level in pregnant rats 24 hours after hypoxic stress. Various changes of the basal glucocorticoid level were found in the offspring after antenatal stress. Changes were mostly found in female offspring.
Bibliography:http://dx.doi.org/10.1134/S1062359011010109
ISSN:1062-3590
1608-3059
DOI:10.1134/S1062359011010109