Plasma deposited metal Schiff-base compounds as antimicrobials

This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial...

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Bibliographic Details
Published inNew journal of chemistry Vol. 35; no. 7; pp. 1477 - 1484
Main Authors Poulter, Neil, Donaldson, Matthew, Mulley, Geraldine, Duque, Luis, Waterfield, Nicholas, Shard, Alex G., Spencer, Steve, Jenkins, A. Tobias A., Johnson, Andrew L.
Format Journal Article
LanguageEnglish
Published 2011
Subjects
Antimicrobial activity
Antimicrobial agents
Copper
Crystal structure
Fabrics
FliM protein
Heavy metals
Pseudomonas aeruginosa
Staphylococcus aureus
Zinc
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Summary:This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial efficacy of the two compounds were observed, suggesting possible mechanisms for antimicrobial activity. The ZSB system was plasma deposited under various pulse conditions onto non-woven fabric, and the antimicrobial efficacy of the resultant film measured for Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest the potential utility of this compound as an effective antimicrobial thin film, and confirm the critical role the ligands play in effecting antimicrobial activity.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:1144-0546
1369-9261
DOI:10.1039/c1nj20091g