FeNH4(SO4)2·12H2O (alum)-catalyzed preparation of 1,4-dihydropyridines: improved conditions for the Hantzsch reaction

FeNH 4 (SO 4 ) 2 ·12H 2 O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity. Graphical abstract

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Published in	Monatshefte für Chemie Vol. 143; no. 6; pp. 931 - 933
Main Authors	Mohammadi, Ali A., Hadadzahmatkesh, Armin, Asghariganjeh, Mohammad R.
Format	Journal Article
Language	English
Published	Vienna Springer Vienna 2012
Subjects	Analytical Chemistry Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Original Paper Physical Chemistry Theoretical and Computational Chemistry Multi-component reactions 12H FeNH ) Hantzsch reaction SO 1,4-Dihydropyridines O
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Abstract	FeNH 4 (SO 4 ) 2 ·12H 2 O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity. Graphical abstract
AbstractList	FeNH 4 (SO 4 ) 2 ·12H 2 O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity. Graphical abstract ABSTRACTFeNH4(SO4)2·12H2O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity. GRAPHICAL ABSTRACT
Author	Mohammadi, Ali A. Hadadzahmatkesh, Armin Asghariganjeh, Mohammad R.
Author_xml	– sequence: 1 givenname: Ali A. surname: Mohammadi fullname: Mohammadi, Ali A. email: aliamohammadi@iaus.ac.ir organization: Department of Chemistry, Sabzevar Branch, Islamic Azad University – sequence: 2 givenname: Armin surname: Hadadzahmatkesh fullname: Hadadzahmatkesh, Armin organization: Department of Chemistry, Sabzevar Branch, Islamic Azad University – sequence: 3 givenname: Mohammad R. surname: Asghariganjeh fullname: Asghariganjeh, Mohammad R. organization: Department of Chemistry, Omidieh Branch, Islamic Azad University
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Cites_doi	10.1248/cpb.56.1002 10.1016/S0040-4039(00)00660-2 10.1021/jo0342830 10.1081/SCC-120015771 10.1055/s-2007-990839 10.1016/j.tetlet.2007.11.003 10.2174/138620709788489073 10.1016/j.tetlet.2007.03.130 10.1016/j.molcata.2006.09.004 10.1016/j.tet.2006.12.074 10.1016/j.tet.2005.01.008 10.1055/s-0028-1087296 10.1016/0223-5234(92)90006-M 10.1358/dof.1992.017.06.175816 10.1002/jhet.5570440228 10.3998/ark.5550190.0009.c15 10.1021/jo049138g 10.1248/cpb.54.1044 10.1055/s-2007-983839
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Keywords	Multi-component reactions 12H FeNH ) Hantzsch reaction SO 1,4-Dihydropyridines O
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Snippet	FeNH 4 (SO 4 ) 2 ·12H 2 O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford... ABSTRACTFeNH4(SO4)2·12H2O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford...
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SubjectTerms	Analytical Chemistry Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Original Paper Physical Chemistry Theoretical and Computational Chemistry
Title	FeNH4(SO4)2·12H2O (alum)-catalyzed preparation of 1,4-dihydropyridines: improved conditions for the Hantzsch reaction
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