CD59‐deficient bone marrow erythroid cells from rats treated with procarbazine and propyl‐nitrosourea have mutations in the Pig‐a gene - Revollo, Javier R.; Dad, Azra; Pearce, Mason G.; Mittelstaedt, Roberta A.; Casildo, Andrea; Lapidus, Rena G.; Robison, Timothy W.; Dobrovolsky, Vasily N. (Environmental and molecular mutagenesis, 2020)
Keywords: Amino acid sequence; Animals; Antineoplastic Agents - toxicity; Bone marrow; Bone Marrow Cells - drug effects; Bone Marrow Cells - immunology; Carcinogens; CD59 antigen; CD59 Antigens - genetics; Deficient mutant; Erythrocytes; Erythroid cells; Flow cytometry; Genotype & phenotype; glycosyl phosphatidylinositol; Male; Membrane Proteins - genetics; Mutagens; Mutation; Next-generation sequencing; Nitrosourea Compounds - toxicity; Osteoprogenitor cells; Peripheral blood; Phenotypes; Point mutation; Procarbazine; Procarbazine - toxicity; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; red blood cells; sequencing; Swine; red blood cells; glycosyl phosphatidylinositol; flow cytometry; sequencing