Exploring cardiovascular health and alternative biological fluid sampling methods in extreme environments: Lessons from a 12-day Mars analog mission

• Published in: Acta astronautica Vol. 234; pp. 194 - 206
• Main Authors: Derobertmasure, A., Toh, L.S., Kafi, L., Obeid, H., Burk, J., Decadi, A., Renaud, C., Villa-Massone, J., Davidson, K., kennedy, E., Bruno, R.M., Chhun, S., Boutouyrie, P.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.09.2025
• Subjects: Arterial health; Dried blood spot; Dried urine spot; Mars analog mission; Pulse wave velocity; Space pharmacology; Dried blood spot; PAX; UMphe; BP; AUC; LC-MS/MS; ESA; DBS; t1/2; Arterial health; Dried urine spot; MBP; PMphe; TDM; BMI; IMphe; SBP; Mars analog mission; DUS; MR; NASA; ISS; CAF; BLEO; DMS; SIC; SOL; CV; Kel; PD; ft-PWV; CYP1A2; Dtf; LEO; Pulse wave velocity; PCM; PK; MDRS; Space pharmacology

Long-term spaceflights (>6 months) induces early vascular aging in astronauts, compromising space missions, particularly as new individuals with unique profiles are expected to fly. The lack of vascular data in astronauts necessitates to test non-invasive and portable techniques to assess arteria...