Antitumour activity of oleanolic acid: A systematic review and meta‑analysis

• Published in: Oncology letters Vol. 28; no. 6; p. 582
• Main Authors: Zeng, Ying, Wang, Zhonglian, Zhang, Jing, Jian, Wei, Fu, Qiaofen
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications UK Ltd 01.12.2024; D.A. Spandidos
• Subjects: Acids; Bias; Bioavailability; Cancer therapies; Cell cycle; Drug dosages; Drug resistance; Intervention; Laboratory animals; Meta-analysis; Mortality; Natural products; Radiation; Software; Systematic review; United States > US; Netherlands; pentacyclic triterpenes; meta-analysis; animal tumour model; neoplasms; oleanolic acid; biological products

Oleanolic acid (OA), a compound known for its potent antitumour properties, has been the subject of investigations in both cell and animal models. Although OA has good biological activity, its low water solubility and bioavailability limit its therapeutic use, and therefore translating the potential...