The cancer genome atlas - TCGA molecular classification: A changing paradigm in the management of endometrial cancers

• Published in: Current medicine research and practice Vol. 13; no. 2; pp. 69 - 73
• Main Author: Modi, Rahul
• Format: Journal Article
• Language: English
• Published: Wolters Kluwer India Pvt. Ltd 01.03.2023; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Adjuvant treatment; Analysis; Cancer; Endometrial cancer; Evidence-based medicine; Genetic aspects; Genomics; Health aspects; micro-satellite instability; molecular classification; Oncology, Experimental; p53 mutation; pole mutation; p53 mutation; POLE mutation; Endometrial cancer; micro-satellite instability; molecular classification

Conventionally, endometrial cancers have been risk-stratified as per the clinco-pathological factors. The Cancer Genome Atlas project identified four distinct molecular subtypes within endometrial cancers which further lead to the clinical validation of molecular classification by various research g...