Clinically compatible subject‐specific dynamic parallel transmit pulse design for homogeneous fat saturation and water‐excitation at 7T: Proof‐of‐concept for CEST MRI of the brain

• Published in: Magnetic resonance in medicine Vol. 89; no. 1; pp. 77 - 94
• Main Authors: Lévy, Simon, Herrler, Jürgen, Liebert, Andrzej, Tkotz, Katharina, Fabian, Moritz S., Eisen, Christian, Grodzki, David, Uder, Michael, Dörfler, Arnd, Zaiss, Moritz, Nagel, Armin M.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.01.2023
• Subjects: Algorithms; Brain; Brain - diagnostic imaging; Cerebellum; Contrast Media; Excitation; Frequency dependence; Homogeneity; Humans; Lipids; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Pulse duration; Pulse shape; Root-mean-square errors; Saturation; Selectivity; Sinuses; Trajectory optimization; Water; water-excitation; fat saturation; 7T MRI; fat suppression; CEST; parallel transmission; dynamic pulse design

To evaluate the benefits and challenges of dynamic parallel transmit (pTx) pulses for fat saturation (FS) and water-excitation (WE), in the context of CEST MRI. "Universal" k -points (for FS) and spiral non-selective (for WE) trajectories were optimized offline for flip angle (FA) homogene...