Na+/H+ and Cl–/HCO3 –-antiporters of bovine pigmented ciliary epithelial cells

• Published in: Pflügers Archiv Vol. 440; no. 5; pp. 667 - 678
• Main Authors: Counillon, L., Touret, Nicolas, Bidet, Michel, Peterson-Yantorno, K., Coca-Prados, M., Stuart-Tilley, Alan, Wilhelm, Sabine, Alper, S.L., Civan, M.M.
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer Nature B.V 01.09.2000

Medical therapy of glaucoma commonly aims at slowing aqueous humor formation by the ocular ciliary epithelial bilayer, but underlying mechanisms are poorly understood. The first step in secretion is NaCl uptake from the stroma into the pigmented ciliary epithelial (PE) cell layer by electroneutral t...