Long-term outcomes of elderly kidney transplant recipients

The number of elderly patients with chronic kidney disease increases progressively, challenging the allocation algorithms in a scenario of organ shortage for transplantation. To evaluate the impact of age on patient and graft survival. Evolution of all 366 patients greater than 60 years transplanted...

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Bibliographic Details
Published inJornal Brasileiro de nefrologia Vol. 37; no. 2; p. 212
Main Authors Orlandi, Paula Ferreira, Cristelli, Marina Pontello, Aldworth, Carolina Araujo Rodrigues, Freitas, Taina Veras de Sandes, Felipe, Claudia Rosso, Silva Junior, Helio Tedesco, Pestana, Jose Osmar Medina de Abreu
Format Journal Article
LanguageEnglish
Published Brazil 01.04.2015
Subjects
Adolescent
Adult
Age Factors
Aged
Cohort Studies
Female
Graft Survival
Humans
Kidney Transplantation
Male
Middle Aged
Retrospective Studies
Time Factors
Treatment Outcome
Young Adult
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Summary:The number of elderly patients with chronic kidney disease increases progressively, challenging the allocation algorithms in a scenario of organ shortage for transplantation. To evaluate the impact of age on patient and graft survival. Evolution of all 366 patients greater than 60 years transplanted between 1998 and 2010 was analyzed versus a control group of 366 younger patients matched for gender, type of donor (living or deceased) and year of transplantation. Diabetes mellitus (HR 1.8; IC 1.2-2.6; p = 0,003) and prioritization (HR 2.9; IC 1.2-2.6; p < 0,001), but not age, were independent factors for kidney graft loss. Advanced age was not related to negative outcomes after kidney transplantation, after excluding recipient death as a cause of allograft loss. Higher mortality rate in this group was associated to a higher frequency of comorbidities, especially diabetes mellitus.
ISSN:0101-2800
2175-8239
DOI:10.5935/0101-2800.20150034